NBP233142V
Kappa Light Chain Antibody (L1C1), DyLight 405, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP233142V-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP233142V - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Kappa Light Chain
Classification
Monoclonal
Conjugate
DyLight 405
Gene Alias
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Host Species
Mouse
Molecular Weight of Antigen
22.5 kDa
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage
Store at 4C in the dark.
Isotype
IgG1 κ
Applications
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone
L1C1
Dilution
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols
IGKC
Immunogen
B lymphoma cells
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
3514
Target Species
Human
Form
Purified
Description
- Description Kappa Light Chain Monoclonal specifically detects Kappa Light Chain in Human samples
- It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Kappa Light Chain
Classification: Monoclonal
Conjugate: DyLight 405
Gene Alias: HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Host Species: Mouse
Molecular Weight of Antigen: 22.5 kDa
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: L1C1
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols: IGKC
Immunogen: B lymphoma cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3514
Target Species: Human
Form: Purified
Antigen:
Kappa Light Chain
Classification:
Monoclonal
Conjugate:
DyLight 405
Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Host Species:
Mouse
Molecular Weight of Antigen:
22.5 kDa
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
L1C1
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols:
IGKC
Immunogen:
B lymphoma cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3514
Target Species:
Human
Form:
Purified
Antigen: Kappa Light Chain
Classification: Monoclonal
Conjugate: Alexa Fluor 405
Gene Alias: HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Host Species: Mouse
Molecular Weight of Antigen: 22.5 kDa
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: L1C1
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols: IGKC
Immunogen: B lymphoma cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3514
Target Species: Human
Form: Purified
Antigen:
Kappa Light Chain
Classification:
Monoclonal
Conjugate:
Alexa Fluor 405
Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Host Species:
Mouse
Molecular Weight of Antigen:
22.5 kDa
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
L1C1
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols:
IGKC
Immunogen:
B lymphoma cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3514
Target Species:
Human
Form:
Purified
Antigen: Kappa Light Chain
Classification: Monoclonal
Conjugate: Alexa Fluor 700
Gene Alias: HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Host Species: Mouse
Molecular Weight of Antigen: 22.5 kDa
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: L1C1
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols: IGKC
Immunogen: B lymphoma cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 3514
Target Species: Human
Form: Purified
Antigen:
Kappa Light Chain
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Host Species:
Mouse
Molecular Weight of Antigen:
22.5 kDa
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
L1C1
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols:
IGKC
Immunogen:
B lymphoma cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
3514
Target Species:
Human
Form:
Purified
Antigen: CD45RA
Classification: Monoclonal
Conjugate: Unconjugated
Gene Alias: B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.1 mg
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 205kDa-220kDa, identified as CD45RA [Workshop V; Code CD45.38]. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This monoclonal antibody is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2a κ
Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone: 158-4D3
Dilution: Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, CyTOF-ready
Gene Symbols: PTPRC
Immunogen: Stimulated human leukocytes were used as immunogen to generate the CD45RA antibody.
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 5788
Target Species: Human, Primate
Form: Purified
Antigen:
CD45RA
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 205kDa-220kDa, identified as CD45RA [Workshop V; Code CD45.38]. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This monoclonal antibody is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG2a κ
Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone:
158-4D3
Dilution:
Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, CyTOF-ready
Gene Symbols:
PTPRC
Immunogen:
Stimulated human leukocytes were used as immunogen to generate the CD45RA antibody.
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
5788
Target Species:
Human, Primate
Form:
Purified