NBP233159P

CD46 Antibody (122.2), PerCP, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP233159P-Each-of-1 In Stock ₹ 56,298.48

NBP233159P - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

CD46

Classification

Monoclonal

Conjugate

PerCP

Gene Alias

AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

122.2

Dilution

Flow Cytometry 1:10-1:1000

Gene Symbols

CD46

Immunogen

Recombinant human CD46 protein (Uniprot: P15529)

Quantity

0.1 mL

Research Discipline

Cancer, Cell Biology, Cellular Markers, Immunology

Gene ID (Entrez)

4179

Target Species

Human

Form

Purified

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Description

  • CD46 Monoclonal specifically detects CD46 in Human samples
  • It is validated for Flow Cytometry.

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Novus Biologicals

NBP233159P

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Antigen:
CD46

Classification:
Monoclonal

Conjugate:
PerCP

Gene Alias:
AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
122.2

Dilution:
Flow Cytometry 1:10-1:1000

Gene Symbols:
CD46

Immunogen:
Recombinant human CD46 protein (Uniprot: P15529)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Immunology

Gene ID (Entrez):
4179

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP233159PE

--


Antigen:
CD46

Classification:
Monoclonal

Conjugate:
PE

Gene Alias:
AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
122.2

Dilution:
Flow Cytometry

Gene Symbols:
CD46

Immunogen:
Recombinant human CD46 protein (Uniprot: P15529)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Immunology

Gene ID (Entrez):
4179

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP233159UV

--


Antigen:
CD46

Classification:
Monoclonal

Conjugate:
DyLight 350

Gene Alias:
AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
122.2

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
CD46

Immunogen:
Recombinant human CD46 protein (Uniprot: P15529)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Immunology

Gene ID (Entrez):
4179

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP233159W

--


Antigen:
CD46

Classification:
Monoclonal

Conjugate:
Alexa Fluor 405

Gene Alias:
AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
122.2

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
CD46

Immunogen:
Recombinant human CD46 protein (Uniprot: P15529)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Immunology

Gene ID (Entrez):
4179

Target Species:
Human

Form:
Purified