NBP233180Y

TAG-72 Antibody (B72.3), Alexa Fluor™ 647, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP233180Y-Each-of-1 In Stock ₹ 55,271.76

NBP233180Y - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

TAG-72

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Gene Alias

CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Immunogen

A membrane enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for the TAG-72 (B72.3) antibody.

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Applications

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

B72.3

Dilution

Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

182875

Target Species

Human, Rat, Bovine, Canine, Hamster

Form

Purified

Description

  • TAG-72 Monoclonal specifically detects TAG-72 in Human, Rat, Bovine, Canine, Hamster samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

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Novus Biologicals

NBP233180Y

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Antigen:
TAG-72

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene Alias:
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Immunogen:
A membrane enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for the TAG-72 (B72.3) antibody.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
B72.3

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
182875

Target Species:
Human, Rat, Bovine, Canine, Hamster

Form:
Purified

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Novus Biologicals

NBP233182

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Antigen:
VCAM-1/CD106

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1

Immunogen:
Stimulated HUVEC cells were used as the immunogen for the VCAM1 (CD106) antibody.

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1 κ

Applications:
Western Blot, ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
1.4C3

Dilution:
Western Blot, ELISA, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
7412

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP233182C

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Antigen:
VCAM-1/CD106

Classification:
Monoclonal

Conjugate:
DyLight 650

Gene Alias:
CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1

Immunogen:
Stimulated HUVEC cells were used as the immunogen for the VCAM1 (CD106) antibody.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
1.4C3

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
7412

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP233182FR

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Antigen:
VCAM-1/CD106

Classification:
Monoclonal

Conjugate:
DyLight 680

Gene Alias:
CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1

Immunogen:
Stimulated HUVEC cells were used as the immunogen for the VCAM1 (CD106) antibody.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
1.4C3

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
7412

Target Species:
Human

Form:
Purified