NBP233188
Cytokeratin 17 Antibody (E3 (same as Ks17.E3)) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP233188-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP233188 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Cytokeratin 17
Classification
Monoclonal
Concentration
1.0 mg/mL
Dilution
ELISA 1-5ug/ml for coating
Gene Symbols
KRT17
Immunogen
Cytoskeletal fraction of rat colon epithelium (Uniprot: Q04695)
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as 'epithelial stem cell' marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype
IgG2b κ
Applications
ELISA
Clone
E3 (same as Ks17.E3)
Conjugate
Unconjugated
Gene Alias
39.1, CK-17, cytokeratin-17, K17, keratin 17, keratin, type I cytoskeletal 17, keratin-17, PC, PC2, PCHC1
Host Species
Mouse
Molecular Weight of Antigen
46 kDa
Quantity
0.1 mg
Research Discipline
Cancer
Gene ID (Entrez)
3872
Target Species
Human, Rat, Porcine, Bovine, Goat
Form
Purified
Related Products
Description
- Cytokeratin 17 Monoclonal specifically detects Cytokeratin 17 in Human, Rat, Porcine, Bovine, Goat samples
- It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Compare Similar Items
Show Difference
Antigen: Cytokeratin 17
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: ELISA 1-5ug/ml for coating
Gene Symbols: KRT17
Immunogen: Cytoskeletal fraction of rat colon epithelium (Uniprot: Q04695)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as 'epithelial stem cell' marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2b κ
Applications: ELISA
Clone: E3 (same as Ks17.E3)
Conjugate: Unconjugated
Gene Alias: 39.1, CK-17, cytokeratin-17, K17, keratin 17, keratin, type I cytoskeletal 17, keratin-17, PC, PC2, PCHC1
Host Species: Mouse
Molecular Weight of Antigen: 46 kDa
Quantity: 0.1 mg
Research Discipline: Cancer
Gene ID (Entrez): 3872
Target Species: Human, Rat, Porcine, Bovine, Goat
Form: Purified
Antigen:
Cytokeratin 17
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
ELISA 1-5ug/ml for coating
Gene Symbols:
KRT17
Immunogen:
Cytoskeletal fraction of rat colon epithelium (Uniprot: Q04695)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as 'epithelial stem cell' marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG2b κ
Applications:
ELISA
Clone:
E3 (same as Ks17.E3)
Conjugate:
Unconjugated
Gene Alias:
39.1, CK-17, cytokeratin-17, K17, keratin 17, keratin, type I cytoskeletal 17, keratin-17, PC, PC2, PCHC1
Host Species:
Mouse
Molecular Weight of Antigen:
46 kDa
Quantity:
0.1 mg
Research Discipline:
Cancer
Gene ID (Entrez):
3872
Target Species:
Human, Rat, Porcine, Bovine, Goat
Form:
Purified
Antigen: Bcl-10
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: ELISA 1-5ug/ml for coating
Gene Symbols: BCL10
Immunogen: Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1 κ
Applications: ELISA
Clone: BL10/411
Conjugate: Unconjugated
Gene Alias: B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Host Species: Mouse
Molecular Weight of Antigen: 33 kDa
Quantity: 0.1 mg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): 8915
Target Species: Human
Form: Purified
Antigen:
Bcl-10
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
ELISA 1-5ug/ml for coating
Gene Symbols:
BCL10
Immunogen:
Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1 κ
Applications:
ELISA
Clone:
BL10/411
Conjugate:
Unconjugated
Gene Alias:
B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Host Species:
Mouse
Molecular Weight of Antigen:
33 kDa
Quantity:
0.1 mg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
8915
Target Species:
Human
Form:
Purified
Antigen: Bcl-10
Classification: Monoclonal
Concentration: __
Dilution: ELISA
Gene Symbols: BCL10
Immunogen: Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: ELISA
Clone: BL10/411
Conjugate: Biotin
Gene Alias: B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Host Species: Mouse
Molecular Weight of Antigen: 33 kDa
Quantity: 0.1 mL
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): 8915
Target Species: Human
Form: Purified
Antigen:
Bcl-10
Classification:
Monoclonal
Concentration:
__
Dilution:
ELISA
Gene Symbols:
BCL10
Immunogen:
Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
ELISA
Clone:
BL10/411
Conjugate:
Biotin
Gene Alias:
B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Host Species:
Mouse
Molecular Weight of Antigen:
33 kDa
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
8915
Target Species:
Human
Form:
Purified
Antigen: Bcl-10
Classification: Monoclonal
Concentration: __
Dilution: ELISA
Gene Symbols: BCL10
Immunogen: Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: ELISA
Clone: BL10/411
Conjugate: DyLight 650
Gene Alias: B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Host Species: Mouse
Molecular Weight of Antigen: 33 kDa
Quantity: 0.1 mL
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): 8915
Target Species: Human
Form: Purified
Antigen:
Bcl-10
Classification:
Monoclonal
Concentration:
__
Dilution:
ELISA
Gene Symbols:
BCL10
Immunogen:
Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
ELISA
Clone:
BL10/411
Conjugate:
DyLight 650
Gene Alias:
B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Host Species:
Mouse
Molecular Weight of Antigen:
33 kDa
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
8915
Target Species:
Human
Form:
Purified