NBP233190Z

Bcl-10 Antibody (BL10/411), Alexa Fluor™ 700, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP233190Z-Each-of-1 In Stock ₹ 55,271.76

NBP233190Z - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Bcl-10

Classification

Monoclonal

Conjugate

Alexa Fluor 700

Gene Alias

B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB

Host Species

Mouse

Molecular Weight of Antigen

33 kDa

Quantity

0.1 mL

Research Discipline

Apoptosis, Cancer

Gene ID (Entrez)

8915

Target Species

Human

Form

Purified

Applications

ELISA

Clone

BL10/411

Dilution

ELISA

Gene Symbols

BCL10

Immunogen

Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Description

  • Bcl-10 Monoclonal specifically detects Bcl-10 in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NBP233190Z

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Antigen:
Bcl-10

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Gene Alias:
B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB

Host Species:
Mouse

Molecular Weight of Antigen:
33 kDa

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
8915

Target Species:
Human

Form:
Purified

Applications:
ELISA

Clone:
BL10/411

Dilution:
ELISA

Gene Symbols:
BCL10

Immunogen:
Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233192

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Antigen:
CD117/c-kit

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mg

Research Discipline:
Cancer, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Phospho Specific, Protein Kinase, Signal Transduction, Stem Cell Markers, Tyrosine Kinases

Gene ID (Entrez):
3815

Target Species:
Human

Form:
Purified

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
C117/370

Dilution:
ELISA 1-5ug/ml for coating, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Symbols:
KIT

Immunogen:
Recombinant human CD117/c-kit protein (Uniprot: P10721)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233192B

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Antigen:
CD117/c-kit

Classification:
Monoclonal

Conjugate:
Biotin

Gene Alias:
CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Research Discipline:
Cancer, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Phospho Specific, Protein Kinase, Signal Transduction, Stem Cell Markers, Tyrosine Kinases

Gene ID (Entrez):
3815

Target Species:
Human

Form:
Purified

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
C117/370

Dilution:
ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
KIT

Immunogen:
Recombinant human CD117/c-kit protein (Uniprot: P10721)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP233192FR

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Antigen:
CD117/c-kit

Classification:
Monoclonal

Conjugate:
DyLight 680

Gene Alias:
CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Research Discipline:
Cancer, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Phospho Specific, Protein Kinase, Signal Transduction, Stem Cell Markers, Tyrosine Kinases

Gene ID (Entrez):
3815

Target Species:
Human

Form:
Purified

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
C117/370

Dilution:
ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
KIT

Immunogen:
Recombinant human CD117/c-kit protein (Uniprot: P10721)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ