NBP234236B

Lambda Light Chain Antibody (LcN-2 + ICO-106), Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

Lambda Light Chain

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

IGLC, immunoglobulin lambda constant group

Host Species

Mouse

Molecular Weight of Antigen

22.5 kDa

Quantity

0.2 mg

Primary or Secondary

Primary

Test Specificity

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage

Store at 4C.

Isotype

IgG1, IgG2a κ

Applications

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone

LcN-2 + ICO-106

Dilution

Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.

P01701

Gene Symbols

IGL

Immunogen

Purified human IgG (LcN-2 and ICO-106)

Purification Method

Protein A purified

Regulatory Status

RUO

Gene ID (Entrez)

3536

Target Species

Human

Form

Purified

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Description

  • Lambda Light Chain Monoclonal specifically detects Lambda Light Chain in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

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Fischer Scientific

NBP234236B

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Antigen:
Lambda Light Chain

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
IGLC, immunoglobulin lambda constant group

Host Species:
Mouse

Molecular Weight of Antigen:
22.5 kDa

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4C.

Isotype:
IgG1, IgG2a κ

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
LcN-2 + ICO-106

Dilution:
Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P01701

Gene Symbols:
IGL

Immunogen:
Purified human IgG (LcN-2 and ICO-106)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Gene ID (Entrez):
3536

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP234236F

--


Antigen:
Lambda Light Chain

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
IGLC, immunoglobulin lambda constant group

Host Species:
Mouse

Molecular Weight of Antigen:
22.5 kDa

Quantity:
0.02 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4C.

Isotype:
IgG1, IgG2a κ

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
LcN-2 + ICO-106

Dilution:
Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P01701

Gene Symbols:
IGL

Immunogen:
Purified human IgG (LcN-2 and ICO-106)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Gene ID (Entrez):
3536

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP234237A

--


Antigen:
Chorionic Gonadotropin beta Chain (HCG beta)

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CGB3choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB

Host Species:
Mouse

Molecular Weight of Antigen:
22 kDa

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4C.

Isotype:
IgG1

Applications:
Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
HCGb/459

Dilution:
Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P01233

Gene Symbols:
CGB

Immunogen:
Recombinant hCG beta protein

Purification Method:
Protein A purified

Regulatory Status:
RUO

Gene ID (Entrez):
1082

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP234237B

--


Antigen:
Chorionic Gonadotropin beta Chain (HCG beta)

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CGB3choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB

Host Species:
Mouse

Molecular Weight of Antigen:
22 kDa

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4C.

Isotype:
IgG1

Applications:
Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
HCGb/459

Dilution:
Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P01233

Gene Symbols:
CGB

Immunogen:
Recombinant hCG beta protein

Purification Method:
Protein A purified

Regulatory Status:
RUO

Gene ID (Entrez):
1082

Target Species:
Human

Form:
Purified