NBP234259B

Kappa Light Chain Antibody (KLC709), Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

Kappa Light Chain

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species

Mouse

Molecular Weight of Antigen

22.5 kDa

Quantity

0.2 mg

Research Discipline

Adaptive Immunity, Immunology

Gene ID (Entrez)

3514

Target Species

Human

Form

Purified

Applications

Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

KLC709

Dilution

Simple Western 10 ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.

P01601

Gene Symbols

IGKC

Immunogen

Recombinant human Ig kappa chain

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

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Description

  • Description Kappa Light Chain Monoclonal specifically detects Kappa Light Chain in Human samples
  • It is validated for Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

Compare Similar Items

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Fischer Scientific

NBP234259B

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Antigen:
Kappa Light Chain

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species:
Mouse

Molecular Weight of Antigen:
22.5 kDa

Quantity:
0.2 mg

Research Discipline:
Adaptive Immunity, Immunology

Gene ID (Entrez):
3514

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
KLC709

Dilution:
Simple Western 10 ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P01601

Gene Symbols:
IGKC

Immunogen:
Recombinant human Ig kappa chain

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Fischer Scientific

NBP234259F

--


Antigen:
Kappa Light Chain

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species:
Mouse

Molecular Weight of Antigen:
22.5 kDa

Quantity:
0.02 mg

Research Discipline:
Adaptive Immunity, Immunology

Gene ID (Entrez):
3514

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
KLC709

Dilution:
Simple Western 10 ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P01601

Gene Symbols:
IGKC

Immunogen:
Recombinant human Ig kappa chain

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Fischer Scientific

NBP234260A

--


Antigen:
Insulin

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

Host Species:
Mouse

Molecular Weight of Antigen:
6 kDa

Quantity:
0.1 mg

Research Discipline:
Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers

Gene ID (Entrez):
3630

Target Species:
Human, Mouse, Porcine, Bovine, Rabbit

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
E2-E3 (same as INS04)

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page

Gene Accession No.:
P01308

Gene Symbols:
INS

Immunogen:
Full length (1-84 amino acid) purified pig insulin, conjugated to KLH

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Fischer Scientific

NBP234260B

--


Antigen:
Insulin

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

Host Species:
Mouse

Molecular Weight of Antigen:
6 kDa

Quantity:
0.2 mg

Research Discipline:
Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers

Gene ID (Entrez):
3630

Target Species:
Human, Mouse, Porcine, Bovine, Rabbit

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
E2-E3 (same as INS04)

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page

Gene Accession No.:
P01308

Gene Symbols:
INS

Immunogen:
Full length (1-84 amino acid) purified pig insulin, conjugated to KLH

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ