NBP234286B

Prolactin R Antibody (B6.2 + PRLR742), Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

Prolactin R

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

delta 4-delta 7/11 truncated prolactin receptor, delta 4-SF1b truncated prolactin receptor, hPRL receptor, hPRLrI, PRL-R, prolactin receptor, prolactin receptor delta 7/11, secreted prolactin binding protein

Host Species

Mouse

Molecular Weight of Antigen

70 kDa

Quantity

0.2 mg

Research Discipline

Apoptosis

Gene ID (Entrez)

5618

Target Species

Human

Form

Purified

Applications

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone

B6.2+PRLR742

Dilution

Western Blot 0.25-0.5ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.

P16471

Gene Symbols

PRLR

Immunogen

Semi-purified human prolactin receptor (B6.2); Recombinant human prolactin receptor (PRLR742)

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Content And Storage

Store at 4C.

Isotype

IgG

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Description

  • Prolactin R Monoclonal specifically detects Prolactin R in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

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Fischer Scientific

NBP234286B

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Antigen:
Prolactin R

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
delta 4-delta 7/11 truncated prolactin receptor, delta 4-SF1b truncated prolactin receptor, hPRL receptor, hPRLrI, PRL-R, prolactin receptor, prolactin receptor delta 7/11, secreted prolactin binding protein

Host Species:
Mouse

Molecular Weight of Antigen:
70 kDa

Quantity:
0.2 mg

Research Discipline:
Apoptosis

Gene ID (Entrez):
5618

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
B6.2+PRLR742

Dilution:
Western Blot 0.25-0.5ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P16471

Gene Symbols:
PRLR

Immunogen:
Semi-purified human prolactin receptor (B6.2); Recombinant human prolactin receptor (PRLR742)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Content And Storage:
Store at 4C.

Isotype:
IgG

Img

Fischer Scientific

NBP234286F

--


Antigen:
Prolactin R

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
delta 4-delta 7/11 truncated prolactin receptor, delta 4-SF1b truncated prolactin receptor, hPRL receptor, hPRLrI, PRL-R, prolactin receptor, prolactin receptor delta 7/11, secreted prolactin binding protein

Host Species:
Mouse

Molecular Weight of Antigen:
70 kDa

Quantity:
0.02 mg

Research Discipline:
Apoptosis

Gene ID (Entrez):
5618

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
B6.2+PRLR742

Dilution:
Western Blot 0.25-0.5ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P16471

Gene Symbols:
PRLR

Immunogen:
Semi-purified human prolactin receptor (B6.2); Recombinant human prolactin receptor (PRLR742)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Content And Storage:
Store at 4C.

Isotype:
IgG

Img

Fischer Scientific

NBP234287A

--


Antigen:
CD45

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mg

Research Discipline:
Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Glia Markers, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, MAP Kinase Signaling, Mast Cell Markers, Mesenchymal Stem Cell Markers, Microglia Markers, Modulation of DNA Pools, Myeloid Cell Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
5788

Target Species:
Human, Canine

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
2B11 + PD7/26

Dilution:
Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/mlimmunohistochemistry-Paraffin 0.5-1ug/ml

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Isolated neoplastic cells from T cell lymphoma (2B11); and human peripheral blood lymphocytes maintained in T cell growth factor (PD7/26)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220, 205, 190, 180kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. A positive result with this MAb is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors.

Content And Storage:
Store at 4C.

Isotype:
IgG

Img

Fischer Scientific

NBP234287B

--


Antigen:
CD45

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.2 mg

Research Discipline:
Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Glia Markers, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, MAP Kinase Signaling, Mast Cell Markers, Mesenchymal Stem Cell Markers, Microglia Markers, Modulation of DNA Pools, Myeloid Cell Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
5788

Target Species:
Human, Canine

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
2B11 + PD7/26

Dilution:
Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/mlimmunohistochemistry-Paraffin 0.5-1ug/ml

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Isolated neoplastic cells from T cell lymphoma (2B11); and human peripheral blood lymphocytes maintained in T cell growth factor (PD7/26)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220, 205, 190, 180kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. A positive result with this MAb is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors.

Content And Storage:
Store at 4C.

Isotype:
IgG