NBP234318B

CD8 Antibody (C8/468 + C8/144B), Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

CD8 alpha

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

CD8, CD8 antigen, alpha polypeptide (p32), CD8a antigen, CD8a molecule, Leu2, Leu2 T-lymphocyte antigen, MAL, OKT8 T-cell antigen, p32, RPA-T8, RPA-T8 antibody flow, RPA-T8 CD8, RPA-T8 Clone, RPA-T8 Flow, T cell co-receptor, T8 T-cell antigen, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

Host Species

Mouse

Molecular Weight of Antigen

32 kDa

Quantity

0.2 mg

Research Discipline

Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers

Gene ID (Entrez)

925

Target Species

Human

Form

Purified

Applications

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone

C8/468 + C8/144B

Dilution

Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/mlimmunohistochemistry-Paraffin 0.5-1ug/ml, SDS-Page

Gene Accession No.

P01732

Gene Symbols

CD8A

Immunogen

Human CD8 recombinant protein (C8/468); A 13 amino acid peptide from C-terminal cytoplasmic domain of alpha chain of human CD8 molecule (C8/144B)

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.

Content And Storage

Store at 4C.

Isotype

IgG

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Description

  • CD8 Monoclonal specifically detects CD8 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Fischer Scientific

NBP234318B

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Antigen:
CD8 alpha

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CD8, CD8 antigen, alpha polypeptide (p32), CD8a antigen, CD8a molecule, Leu2, Leu2 T-lymphocyte antigen, MAL, OKT8 T-cell antigen, p32, RPA-T8, RPA-T8 antibody flow, RPA-T8 CD8, RPA-T8 Clone, RPA-T8 Flow, T cell co-receptor, T8 T-cell antigen, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

Host Species:
Mouse

Molecular Weight of Antigen:
32 kDa

Quantity:
0.2 mg

Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
925

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
C8/468 + C8/144B

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/mlimmunohistochemistry-Paraffin 0.5-1ug/ml, SDS-Page

Gene Accession No.:
P01732

Gene Symbols:
CD8A

Immunogen:
Human CD8 recombinant protein (C8/468); A 13 amino acid peptide from C-terminal cytoplasmic domain of alpha chain of human CD8 molecule (C8/144B)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.

Content And Storage:
Store at 4C.

Isotype:
IgG

Img

Fischer Scientific

NBP234318F

--


Antigen:
CD8 alpha

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CD8, CD8 antigen, alpha polypeptide (p32), CD8a antigen, CD8a molecule, Leu2, Leu2 T-lymphocyte antigen, MAL, OKT8 T-cell antigen, p32, RPA-T8, RPA-T8 antibody flow, RPA-T8 CD8, RPA-T8 Clone, RPA-T8 Flow, T cell co-receptor, T8 T-cell antigen, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

Host Species:
Mouse

Molecular Weight of Antigen:
32 kDa

Quantity:
0.02 mg

Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
925

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
C8/468 + C8/144B

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/mlimmunohistochemistry-Paraffin 0.5-1ug/ml, SDS-Page

Gene Accession No.:
P01732

Gene Symbols:
CD8A

Immunogen:
Human CD8 recombinant protein (C8/468); A 13 amino acid peptide from C-terminal cytoplasmic domain of alpha chain of human CD8 molecule (C8/144B)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.

Content And Storage:
Store at 4C.

Isotype:
IgG

Img

Fischer Scientific

NBP234331A

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Antigen:
CDC2/CDK1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CDC28A, CDC2MGC111195, cell cycle controller CDC2, Cell division control protein 2 homolog, Cell division protein kinase 1, cyclin-dependent kinase 1, DKFZp686L20222, EC 2.7.11.22, EC 2.7.11.23, G1 to S and G2 to M, p34 protein kinase, P34CDC2

Host Species:
Mouse

Molecular Weight of Antigen:
34 kDa

Quantity:
0.1 mg

Research Discipline:
Breast Cancer, Cancer, Cell Cycle and Replication, Core ESC Like Genes, Mitotic Regulators, Stem Cell Markers

Gene ID (Entrez):
983

Target Species:
Human, Bovine, Mustelid, Primate, Drosophila (Negative), Mouse (Negative), Rat (Negative), Xenopus (Negative)

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
POH-1; same as cdc2.1

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen 1-2ug/ml, SDS-Page

Gene Accession No.:
P06493

Gene Symbols:
CDK1

Immunogen:
Purified recombinant human p34cdc2 fusion protein

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1/ p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1/ p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

Img

Fischer Scientific

NBP234331B

--


Antigen:
CDC2/CDK1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CDC28A, CDC2MGC111195, cell cycle controller CDC2, Cell division control protein 2 homolog, Cell division protein kinase 1, cyclin-dependent kinase 1, DKFZp686L20222, EC 2.7.11.22, EC 2.7.11.23, G1 to S and G2 to M, p34 protein kinase, P34CDC2

Host Species:
Mouse

Molecular Weight of Antigen:
34 kDa

Quantity:
0.2 mg

Research Discipline:
Breast Cancer, Cancer, Cell Cycle and Replication, Core ESC Like Genes, Mitotic Regulators, Stem Cell Markers

Gene ID (Entrez):
983

Target Species:
Human, Bovine, Mustelid, Primate, Drosophila (Negative), Mouse (Negative), Rat (Negative), Xenopus (Negative)

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
POH-1; same as cdc2.1

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen 1-2ug/ml, SDS-Page

Gene Accession No.:
P06493

Gene Symbols:
CDK1

Immunogen:
Purified recombinant human p34cdc2 fusion protein

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1/ p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1/ p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ