NBP234409Z

IGF-I/IGF-1 Antibody (SPM406), Alexa Fluor™ 700, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP234409Z-Each-of-1 In Stock ₹ 55,271.76

NBP234409Z - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

IGF-I/IGF-1

Classification

Monoclonal

Conjugate

Alexa Fluor 700

Gene Alias

IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C

Host Species

Mouse

Molecular Weight of Antigen

7.6 kDa

Quantity

0.1 mL

Research Discipline

Cell Cycle and Replication

Gene ID (Entrez)

3479

Target Species

Human, Mouse, Rat, Rabbit

Form

Purified

Applications

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

SPM406

Dilution

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Symbols

IGF1

Immunogen

Purified human IGF-I/IGF-1 protein (Uniprot: P05019)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Description

  • IGF-I/IGF-1 Monoclonal specifically detects IGF-I/IGF-1 in Human, Mouse, Rat, Rabbit samples
  • It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP234409Z

--


Antigen:
IGF-I/IGF-1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Gene Alias:
IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C

Host Species:
Mouse

Molecular Weight of Antigen:
7.6 kDa

Quantity:
0.1 mL

Research Discipline:
Cell Cycle and Replication

Gene ID (Entrez):
3479

Target Species:
Human, Mouse, Rat, Rabbit

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM406

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Symbols:
IGF1

Immunogen:
Purified human IGF-I/IGF-1 protein (Uniprot: P05019)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234410B

--


Antigen:
RBP4/Retinol-Binding Protein 4

Classification:
Monoclonal

Conjugate:
Biotin

Gene Alias:
interstitial, Plasma retinol-binding protein, retinol binding protein 4, plasma, retinol-binding protein 4, plasma

Host Species:
Mouse

Molecular Weight of Antigen:
23 kDa

Quantity:
0.1 mL

Research Discipline:
Cancer, Diabetes Research, Lipid and Metabolism

Gene ID (Entrez):
5950

Target Species:
Human, Mouse, Rat, Goat, Primate, Rabbit

Form:
Purified

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM442

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
RBP4

Immunogen:
Retinol binding protein purified from human plasma

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This monoclonal antibody recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234410C

--


Antigen:
RBP4/Retinol-Binding Protein 4

Classification:
Monoclonal

Conjugate:
DyLight 650

Gene Alias:
interstitial, Plasma retinol-binding protein, retinol binding protein 4, plasma, retinol-binding protein 4, plasma

Host Species:
Mouse

Molecular Weight of Antigen:
23 kDa

Quantity:
0.1 mL

Research Discipline:
Cancer, Diabetes Research, Lipid and Metabolism

Gene ID (Entrez):
5950

Target Species:
Human, Mouse, Rat, Goat, Primate, Rabbit

Form:
Purified

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM442

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
RBP4

Immunogen:
Retinol binding protein purified from human plasma

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This monoclonal antibody recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234410G

--


Antigen:
RBP4/Retinol-Binding Protein 4

Classification:
Monoclonal

Conjugate:
DyLight 488

Gene Alias:
interstitial, Plasma retinol-binding protein, retinol binding protein 4, plasma, retinol-binding protein 4, plasma

Host Species:
Mouse

Molecular Weight of Antigen:
23 kDa

Quantity:
0.1 mL

Research Discipline:
Cancer, Diabetes Research, Lipid and Metabolism

Gene ID (Entrez):
5950

Target Species:
Human, Mouse, Rat, Goat, Primate, Rabbit

Form:
Purified

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM442

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
RBP4

Immunogen:
Retinol binding protein purified from human plasma

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This monoclonal antibody recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ