NBP234432H

FoxP3 Antibody (SPM579), HRP, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP234432H-Each-of-1 In Stock ₹ 56,298.48

NBP234432H - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

FoxP3

Classification

Monoclonal

Conjugate

HRP

Gene Alias

AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked

Host Species

Mouse

Molecular Weight of Antigen

51 kDa

Quantity

0.1 mL

Research Discipline

Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Transcription Factors and Regulators

Gene ID (Entrez)

50943

Target Species

Human, Mouse, Primate

Form

Purified

Applications

ELISA, Immunohistochemistry (Frozen)

Clone

SPM579

Dilution

ELISA, Immunohistochemistry-Frozen

Gene Symbols

FOXP3

Immunogen

Full-length human FoxP3 protein (Uniprot: Q9ZS1)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Description

  • FoxP3 Monoclonal specifically detects FoxP3 in Human, Mouse, Monkey samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP234432H

--


Antigen:
FoxP3

Classification:
Monoclonal

Conjugate:
HRP

Gene Alias:
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked

Host Species:
Mouse

Molecular Weight of Antigen:
51 kDa

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Transcription Factors and Regulators

Gene ID (Entrez):
50943

Target Species:
Human, Mouse, Primate

Form:
Purified

Applications:
ELISA, Immunohistochemistry (Frozen)

Clone:
SPM579

Dilution:
ELISA, Immunohistochemistry-Frozen

Gene Symbols:
FOXP3

Immunogen:
Full-length human FoxP3 protein (Uniprot: Q9ZS1)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234432IR

--


Antigen:
FoxP3

Classification:
Monoclonal

Conjugate:
DyLight 755

Gene Alias:
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked

Host Species:
Mouse

Molecular Weight of Antigen:
51 kDa

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Transcription Factors and Regulators

Gene ID (Entrez):
50943

Target Species:
Human, Mouse, Primate

Form:
Purified

Applications:
Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
SPM579

Dilution:
Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
FOXP3

Immunogen:
Full-length human FoxP3 protein (Uniprot: Q9ZS1)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234432J

--


Antigen:
FoxP3

Classification:
Monoclonal

Conjugate:
APC

Gene Alias:
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked

Host Species:
Mouse

Molecular Weight of Antigen:
51 kDa

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Transcription Factors and Regulators

Gene ID (Entrez):
50943

Target Species:
Human, Mouse, Primate

Form:
Purified

Applications:
Flow Cytometry

Clone:
SPM579

Dilution:
Flow Cytometry

Gene Symbols:
FOXP3

Immunogen:
Full-length human FoxP3 protein (Uniprot: Q9ZS1)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234432PE

--


Antigen:
FoxP3

Classification:
Monoclonal

Conjugate:
PE

Gene Alias:
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked

Host Species:
Mouse

Molecular Weight of Antigen:
51 kDa

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Transcription Factors and Regulators

Gene ID (Entrez):
50943

Target Species:
Human, Mouse, Primate

Form:
Purified

Applications:
Flow Cytometry

Clone:
SPM579

Dilution:
Flow Cytometry

Gene Symbols:
FOXP3

Immunogen:
Full-length human FoxP3 protein (Uniprot: Q9ZS1)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ