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NBP234432Y

FoxP3 Antibody (SPM579), Alexa Fluor™ 647, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP234432Y-Each-of-1 In Stock ₹ 56,298.48

NBP234432Y - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

FoxP3

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Gene Alias

AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked

Host Species

Mouse

Molecular Weight of Antigen

51 kDa

Quantity

0.1 mL

Research Discipline

Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Transcription Factors and Regulators

Gene ID (Entrez)

50943

Target Species

Human, Mouse, Primate

Form

Purified

Applications

Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone

SPM579

Dilution

Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols

FOXP3

Immunogen

Full-length human FoxP3 protein (Uniprot: Q9ZS1)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Description

  • FoxP3 Monoclonal specifically detects FoxP3 in Human, Mouse, Monkey samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Novus Biologicals

NBP234432Y

--

Antigen:
FoxP3
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Gene Alias:
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked
Host Species:
Mouse
Molecular Weight of Antigen:
51 kDa
Quantity:
0.1 mL
Research Discipline:
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Transcription Factors and Regulators
Gene ID (Entrez):
50943
Target Species:
Human, Mouse, Primate
Form:
Purified
Applications:
Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone:
SPM579
Dilution:
Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Symbols:
FOXP3
Immunogen:
Full-length human FoxP3 protein (Uniprot: Q9ZS1)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234433B

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Antigen:
pan Cytokeratin
Classification:
Monoclonal
Conjugate:
Biotin
Gene Alias:
__
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction
Gene ID (Entrez):
3848
Target Species:
Human, Mouse, Rat, Porcine, Amphibian, Bovine, Guinea Pig, Goat, Primate
Form:
Purified
Applications:
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
SPM583
Dilution:
Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols:
KRT1
Immunogen:
This Cytokeratin, pan Antibody (SPM583) was developed against keratin-enriched preparation from cultured human A431 cells.
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes cytokeratin 4, 5, 6, 8, 10, 13, and 18. This is a broad-spectrum antibody which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234433FR

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Antigen:
pan Cytokeratin
Classification:
Monoclonal
Conjugate:
DyLight 680
Gene Alias:
__
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction
Gene ID (Entrez):
3848
Target Species:
Human, Mouse, Rat, Porcine, Amphibian, Bovine, Guinea Pig, Goat, Primate
Form:
Purified
Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
SPM583
Dilution:
Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols:
KRT1
Immunogen:
This Cytokeratin, pan Antibody (SPM583) was developed against keratin-enriched preparation from cultured human A431 cells.
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes cytokeratin 4, 5, 6, 8, 10, 13, and 18. This is a broad-spectrum antibody which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234433H

--

Antigen:
pan Cytokeratin
Classification:
Monoclonal
Conjugate:
HRP
Gene Alias:
__
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction
Gene ID (Entrez):
3848
Target Species:
Human, Mouse, Rat, Porcine, Amphibian, Bovine, Guinea Pig, Goat, Primate
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
SPM583
Dilution:
Western Blot, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols:
KRT1
Immunogen:
This Cytokeratin, pan Antibody (SPM583) was developed against keratin-enriched preparation from cultured human A431 cells.
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes cytokeratin 4, 5, 6, 8, 10, 13, and 18. This is a broad-spectrum antibody which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ