NBP234507X

Integrin beta 4/CD104 Antibody (UM-A9), Alexa Fluor™ 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP234507X-Each-of-1 In Stock ₹ 55,271.76

NBP234507X - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Integrin beta 4/CD104

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Gene Alias

CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4

Host Species

Mouse

Molecular Weight of Antigen

205 kDa

Quantity

0.1 mL

Research Discipline

Adaptive Immunity, Immunology, Signal Transduction

Gene ID (Entrez)

3691

Target Species

Human

Form

Purified

Applications

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone

UM-A9

Dilution

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols

ITGB4

Immunogen

Human squamous cell carcinoma (UM-SCC1)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Content And Storage

Store at 4C in the dark.

Isotype

IgG2a κ

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Description

  • Integrin beta 4/CD104 Monoclonal specifically detects Integrin beta 4/CD104 in Human samples
  • It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

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Novus Biologicals

NBP234507X

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Antigen:
Integrin beta 4/CD104

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene Alias:
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4

Host Species:
Mouse

Molecular Weight of Antigen:
205 kDa

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Immunology, Signal Transduction

Gene ID (Entrez):
3691

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
UM-A9

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
ITGB4

Immunogen:
Human squamous cell carcinoma (UM-SCC1)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a κ

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NBP234507Y

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Antigen:
Integrin beta 4/CD104

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene Alias:
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4

Host Species:
Mouse

Molecular Weight of Antigen:
205 kDa

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Immunology, Signal Transduction

Gene ID (Entrez):
3691

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
UM-A9

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
ITGB4

Immunogen:
Human squamous cell carcinoma (UM-SCC1)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a κ

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NBP234508B

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Antigen:
CD2

Classification:
Monoclonal

Conjugate:
Biotin

Gene Alias:
CD2 antigen, CD2 antigen (p50), sheep red blood cell receptor, CD2 molecule, Erythrocyte receptor, FLJ46032, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, Rosette receptor, SRBC, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5

Host Species:
Mouse

Molecular Weight of Antigen:
50 kDa

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Apoptosis, Immunology

Gene ID (Entrez):
914

Target Species:
Human

Form:
Purified

Applications:
Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
UMCD2

Dilution:
Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
CD2

Immunogen:
Human Thymocytes/Sezary T cells

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a κ

Img

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NBP234508FR

--


Antigen:
CD2

Classification:
Monoclonal

Conjugate:
DyLight 680

Gene Alias:
CD2 antigen, CD2 antigen (p50), sheep red blood cell receptor, CD2 molecule, Erythrocyte receptor, FLJ46032, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, Rosette receptor, SRBC, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5

Host Species:
Mouse

Molecular Weight of Antigen:
50 kDa

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Apoptosis, Immunology

Gene ID (Entrez):
914

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
UMCD2

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
CD2

Immunogen:
Human Thymocytes/Sezary T cells

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a κ