NBP234515W

Bcl-2 Antibody (100/D5+124), Alexa Fluor™ 405, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP234515W-Each-of-1 In Stock ₹ 56,298.48

NBP234515W - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

Bcl-2

Classification

Monoclonal

Conjugate

Alexa Fluor 405

Gene Alias

apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species

Mouse

Molecular Weight of Antigen

25 kDa

Quantity

0.1 mL

Research Discipline

Apoptosis, Autophagy, Cancer, Cellular Markers, Tumor Suppressors

Gene ID (Entrez)

596

Target Species

Human, Mouse (Negative), Rat (Negative)

Form

Purified

Applications

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

100/D5+124

Dilution

Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols

BCL2

Immunogen

A synthetic peptide, aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 (100/D5 & 124) (Uniprot: P10415)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

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Description

  • Bcl-2 Monoclonal specifically detects Bcl-2 in Human, Mouse (Negative), Rat (Negative) samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP234515W

--


Antigen:
Bcl-2

Classification:
Monoclonal

Conjugate:
Alexa Fluor 405

Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species:
Mouse

Molecular Weight of Antigen:
25 kDa

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Autophagy, Cancer, Cellular Markers, Tumor Suppressors

Gene ID (Entrez):
596

Target Species:
Human, Mouse (Negative), Rat (Negative)

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
100/D5+124

Dilution:
Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
BCL2

Immunogen:
A synthetic peptide, aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 (100/D5 & 124) (Uniprot: P10415)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234516B

--


Antigen:
EBV Early Antigens

Classification:
Monoclonal

Conjugate:
Biotin

Gene Alias:
Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p63, p73L, TP63, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Virus

Form:
Purified

Applications:
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
1108-1

Dilution:
Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
__

Immunogen:
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt's lymphoma sera

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234516IR

--


Antigen:
EBV Early Antigens

Classification:
Monoclonal

Conjugate:
DyLight 755

Gene Alias:
Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p63, p73L, TP63, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Virus

Form:
Purified

Applications:
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
1108-1

Dilution:
Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
__

Immunogen:
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt's lymphoma sera

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234516V

--


Antigen:
EBV Early Antigens

Classification:
Monoclonal

Conjugate:
DyLight 405

Gene Alias:
Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p63, p73L, TP63, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Virus

Form:
Purified

Applications:
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
1108-1

Dilution:
Western Blot, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
__

Immunogen:
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt's lymphoma sera

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ