NBP234547Y

anti-Melanoma Marker (MART-1 + Tyrosinase + gp100), Alexa Fluor 647, Clone: A103 + T311 + HMB45, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP234547Y-Each-of-1 In Stock ₹ 52,277.16

NBP234547Y - Each of 1

₹ 52,277.16

In Stock

Quantity

1

Base Price: ₹ 52,277.16

GST (18%): ₹ 9,409.889

Total Price: ₹ 61,687.049

Antigen

Melanoma Marker (MART-1 + Tyrosinase + gp100)

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Gene Alias

MART1, MART-1, melan-A, MLANA

Immunogen

Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1, IgG2a κ

Applications

Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

A103 + T311 + HMB45

Dilution

Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

2315

Target Species

Human

Form

Purified

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Description

  • Melanoma Marker (MART-1 + Tyrosinase + gp100) Monoclonal specifically detects Melanoma Marker (MART-1 + Tyrosinase + gp100) in Human samples
  • It is validated for Western Blot.

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Show Difference

Img

Novus Biologicals

NBP234547Y

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Antigen:
Melanoma Marker (MART-1 + Tyrosinase + gp100)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene Alias:
MART1, MART-1, melan-A, MLANA

Immunogen:
Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1, IgG2a κ

Applications:
Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
A103 + T311 + HMB45

Dilution:
Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
2315

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP234547Z

--


Antigen:
Melanoma Marker (MART-1 + Tyrosinase + gp100)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Gene Alias:
MART1, MART-1, melan-A, MLANA

Immunogen:
Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1, IgG2a κ

Applications:
Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
A103 + T311 + HMB45

Dilution:
Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
2315

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP234548B

--


Antigen:
Cytokeratin 19

Classification:
Monoclonal

Conjugate:
Biotin

Gene Alias:
CK19, CK-19, cytokeratin 19, Cytokeratin-19,40-kDa keratin intermediate filament, K19cytokeratin-19, K1CS, keratin 19, keratin, type I cytoskeletal 19, keratin, type I, 40-kd, keratin-19, MGC15366

Immunogen:
Human breast cancer MCF-7 cells (A53-B/A2); Human mammary epithelial organoids (BA17)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a λ, IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
A53-B/A2.26 + BA17

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
3880

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP234548G

--


Antigen:
Cytokeratin 19

Classification:
Monoclonal

Conjugate:
DyLight 488

Gene Alias:
CK19, CK-19, cytokeratin 19, Cytokeratin-19,40-kDa keratin intermediate filament, K19cytokeratin-19, K1CS, keratin 19, keratin, type I cytoskeletal 19, keratin, type I, 40-kd, keratin-19, MGC15366

Immunogen:
Human breast cancer MCF-7 cells (A53-B/A2); Human mammary epithelial organoids (BA17)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a λ, IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
A53-B/A2.26 + BA17

Dilution:
Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
3880

Target Species:
Human

Form:
Purified