DOG1/TMEM16A Antibody (DOG-1.1), Biotin, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP234606B-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP234606B - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
DOG1/TMEM16A
Classification
Monoclonal
Conjugate
Biotin
Gene Alias
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
55107
Target Species
Human
Form
Purified
Applications
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone
DOG-1.1
Dilution
Western Blot, Flow Cytometry, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols
ANO1
Immunogen
A synthetic peptide from human canine1/TMEM16A protein (aa 904-986), conjugated to a carrier protein. ( (Uniprot: Q5XXA6 )
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.
Content And Storage
Store at 4C in the dark.
Isotype
IgG1 κ
Related Products
Description
- DOG1/TMEM16A Monoclonal specifically detects DOG1/TMEM16A in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: DOG1/TMEM16A
Classification: Monoclonal
Conjugate: Biotin
Gene Alias: ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 55107
Target Species: Human
Form: Purified
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: DOG-1.1
Dilution: Western Blot, Flow Cytometry, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols: ANO1
Immunogen: A synthetic peptide from human canine1/TMEM16A protein (aa 904-986), conjugated to a carrier protein. ( (Uniprot: Q5XXA6 )
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen: Melanoma Marker (MART-1 + gp100)
Classification: Monoclonal
Conjugate: DyLight 680
Gene Alias: MART1, MART-1
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 2315
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: DT101+ BC199 + HMB45
Dilution: Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols: __
Immunogen: Recombinant hMART-1 protein (DT101& BC199); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b κ, IgG1 κ
Antigen: Melanoma Marker (MART-1 + gp100)
Classification: Monoclonal
Conjugate: HRP
Gene Alias: MART1, MART-1
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 2315
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: DT101+ BC199 + HMB45
Dilution: Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols: __
Immunogen: Recombinant hMART-1 protein (DT101& BC199); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2b κ, IgG1 κ