NBP234618G

VEGFR1/Flt-1 Antibody (FLT1/658), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP234618G-Each-of-1 In Stock ₹ 55,271.76

NBP234618G - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

VEGFR1/Flt-1

Classification

Monoclonal

Conjugate

DyLight 488

Gene Alias

EC 2.7.10, EC 2.7.10.1, FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR1, VEGFR-1

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Applications

ELISA

Clone

FLT1/658

Dilution

ELISA

Gene Symbols

FLT1

Immunogen

Recombinant human VEGFR1/Flt-1 protein (Uniprot: P17948)

Quantity

0.1 mL

Research Discipline

Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, HIF Target Genes, Hypoxia, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez)

2321

Target Species

Human

Form

Purified

Related Products

Img

Novus Biologicals

NBP234618UV

--

Img

Novus Biologicals

NBP234658FR

--

Img

Novus Biologicals

NBP234658IR

--

Img

Novus Biologicals

NBP234658UV

--

Img

Novus Biologicals

NBP234658W

--

Img

Novus Biologicals

NBP234658Y

--

Img

Novus Biologicals

NBP234658Z

--

Img

Novus Biologicals

NBP234553P

--

Description

  • VEGFR1/Flt-1 Monoclonal specifically detects VEGFR1/Flt-1 in Human samples
  • It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP234618G

--


Antigen:
VEGFR1/Flt-1

Classification:
Monoclonal

Conjugate:
DyLight 488

Gene Alias:
EC 2.7.10, EC 2.7.10.1, FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR1, VEGFR-1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
ELISA

Clone:
FLT1/658

Dilution:
ELISA

Gene Symbols:
FLT1

Immunogen:
Recombinant human VEGFR1/Flt-1 protein (Uniprot: P17948)

Quantity:
0.1 mL

Research Discipline:
Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, HIF Target Genes, Hypoxia, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez):
2321

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP234618UV

--


Antigen:
VEGFR1/Flt-1

Classification:
Monoclonal

Conjugate:
DyLight 350

Gene Alias:
EC 2.7.10, EC 2.7.10.1, FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR1, VEGFR-1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
ELISA

Clone:
FLT1/658

Dilution:
ELISA

Gene Symbols:
FLT1

Immunogen:
Recombinant human VEGFR1/Flt-1 protein (Uniprot: P17948)

Quantity:
0.1 mL

Research Discipline:
Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, HIF Target Genes, Hypoxia, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez):
2321

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP234620B

--


Antigen:
FoxP3

Classification:
Monoclonal

Conjugate:
Biotin

Gene Alias:
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
FXP3/197

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
FOXP3

Immunogen:
Recombinant human full-length FoxP3 protein (Uniprot: Q9ZS1)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Transcription Factors and Regulators

Gene ID (Entrez):
50943

Target Species:
Human, Mouse, Primate

Form:
Purified

Img

Novus Biologicals

NBP234620G

--


Antigen:
FoxP3

Classification:
Monoclonal

Conjugate:
DyLight 488

Gene Alias:
AIID, AIIDMGC141961, DIETER, forkhead box P3, Forkhead Box Protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked, IPEX, JM2, MGC141961, MGC141963, PIDX, PIDXMGC141963, Scurfin, XPID, XPIDpolyendocrinopathy, enteropathy, X-linked

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion of the protein. The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
FXP3/197

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
FOXP3

Immunogen:
Recombinant human full-length FoxP3 protein (Uniprot: Q9ZS1)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Cell Biology, Chromatin Research, Immunology, Transcription Factors and Regulators

Gene ID (Entrez):
50943

Target Species:
Human, Mouse, Primate

Form:
Purified