NBP234663V
Ku70/XRCC6 Antibody (KU729), DyLight 405, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP234663V-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP234663V - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Ku70/XRCC6
Classification
Monoclonal
Conjugate
DyLight 405
Gene Alias
5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6
Host Species
Mouse
Molecular Weight of Antigen
75 kDa
Quantity
0.1 mL
Research Discipline
Breast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Non homologous end joining
Gene ID (Entrez)
2547
Target Species
Human, Primate, Chicken (Negative), Mouse (Negative), Rat (Negative)
Form
Purified
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone
KU729
Dilution
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)
Gene Symbols
XRCC6
Immunogen
Nuclear extract of human HL-60 cells
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Content And Storage
Store at 4C in the dark.
Isotype
IgG1 κ
Related Products
Description
- Description Ku70/XRCC6 Monoclonal specifically detects Ku70/XRCC6 in Human, Primate, Chicken (Negative), Mouse (Negative), Rat (Negative) samples
- It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular).
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Antigen: Ku70/XRCC6
Classification: Monoclonal
Conjugate: DyLight 405
Gene Alias: 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 0.1 mL
Research Discipline: Breast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Non homologous end joining
Gene ID (Entrez): 2547
Target Species: Human, Primate, Chicken (Negative), Mouse (Negative), Rat (Negative)
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: KU729
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)
Gene Symbols: XRCC6
Immunogen: Nuclear extract of human HL-60 cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen:
Ku70/XRCC6
Classification:
Monoclonal
Conjugate:
DyLight 405
Gene Alias:
5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
0.1 mL
Research Discipline:
Breast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Non homologous end joining
Gene ID (Entrez):
2547
Target Species:
Human, Primate, Chicken (Negative), Mouse (Negative), Rat (Negative)
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
KU729
Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)
Gene Symbols:
XRCC6
Immunogen:
Nuclear extract of human HL-60 cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Antigen: Ku70/XRCC6
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Gene Alias: 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 0.1 mL
Research Discipline: Breast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Non homologous end joining
Gene ID (Entrez): 2547
Target Species: Human, Primate, Chicken (Negative), Mouse (Negative), Rat (Negative)
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: KU729
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)
Gene Symbols: XRCC6
Immunogen: Nuclear extract of human HL-60 cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen:
Ku70/XRCC6
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Gene Alias:
5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
0.1 mL
Research Discipline:
Breast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Non homologous end joining
Gene ID (Entrez):
2547
Target Species:
Human, Primate, Chicken (Negative), Mouse (Negative), Rat (Negative)
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
KU729
Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)
Gene Symbols:
XRCC6
Immunogen:
Nuclear extract of human HL-60 cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Antigen: Ku70/XRCC6
Classification: Monoclonal
Conjugate: Alexa Fluor 700
Gene Alias: 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 0.1 mL
Research Discipline: Breast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Non homologous end joining
Gene ID (Entrez): 2547
Target Species: Human, Primate, Chicken (Negative), Mouse (Negative), Rat (Negative)
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone: KU729
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)
Gene Symbols: XRCC6
Immunogen: Nuclear extract of human HL-60 cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen:
Ku70/XRCC6
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Gene Alias:
5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
0.1 mL
Research Discipline:
Breast Cancer, Cancer, DNA Double Strand Break Repair, DNA Repair, Non homologous end joining
Gene ID (Entrez):
2547
Target Species:
Human, Primate, Chicken (Negative), Mouse (Negative), Rat (Negative)
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Clone:
KU729
Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular)
Gene Symbols:
XRCC6
Immunogen:
Nuclear extract of human HL-60 cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a dimer of two proteins of 70kDa and ∼80kDa, identified as two subunits of Ku. This monoclonal antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Antigen: Lambda Light Chain
Classification: Monoclonal
Conjugate: DyLight 680
Gene Alias: IGLC, immunoglobulin lambda constant group
Host Species: Mouse
Molecular Weight of Antigen: 22.5 kDa
Quantity: 0.1 mL
Research Discipline: __
Gene ID (Entrez): 3536
Target Species: Human
Form: Purified
Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: LAM03
Dilution: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols: IGLC1
Immunogen: Purified human lambda light chain
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody is specific to Lambda Light Chain of immunoglobulin and shows no cross-reaction with Lambda Light Chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the Lambda Light Chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen:
Lambda Light Chain
Classification:
Monoclonal
Conjugate:
DyLight 680
Gene Alias:
IGLC, immunoglobulin lambda constant group
Host Species:
Mouse
Molecular Weight of Antigen:
22.5 kDa
Quantity:
0.1 mL
Research Discipline:
__
Gene ID (Entrez):
3536
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
LAM03
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols:
IGLC1
Immunogen:
Purified human lambda light chain
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody is specific to Lambda Light Chain of immunoglobulin and shows no cross-reaction with Lambda Light Chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the Lambda Light Chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ