NBP234724W
Thyroglobulin Antibody (TGB04 + TGB05), Alexa Fluor™ 405, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP234724W-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP234724W - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Thyroglobulin
Classification
Monoclonal
Conjugate
Alexa Fluor 405
Gene Alias
AITD3TGN, TDH3, Tg, thyroglobulin
Host Species
Mouse
Molecular Weight of Antigen
660 kDa
Quantity
0.1 mL
Research Discipline
Cancer, Cell Biology
Gene ID (Entrez)
7038
Target Species
Human, Mouse, Rat
Form
Purified
Applications
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone
TGB04 + TGB05
Dilution
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin
Gene Symbols
TG
Immunogen
Human thyroid follicular cells
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m
Content And Storage
Store at 4C in the dark.
Isotype
IgG1 κ
Description
- Thyroglobulin Monoclonal specifically detects Thyroglobulin in Human, Mouse, Rat samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: Thyroglobulin
Classification: Monoclonal
Conjugate: Alexa Fluor 405
Gene Alias: AITD3TGN, TDH3, Tg, thyroglobulin
Host Species: Mouse
Molecular Weight of Antigen: 660 kDa
Quantity: 0.1 mL
Research Discipline: Cancer, Cell Biology
Gene ID (Entrez): 7038
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: TGB04 + TGB05
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin
Gene Symbols: TG
Immunogen: Human thyroid follicular cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen:
Thyroglobulin
Classification:
Monoclonal
Conjugate:
Alexa Fluor 405
Gene Alias:
AITD3TGN, TDH3, Tg, thyroglobulin
Host Species:
Mouse
Molecular Weight of Antigen:
660 kDa
Quantity:
0.1 mL
Research Discipline:
Cancer, Cell Biology
Gene ID (Entrez):
7038
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
TGB04 + TGB05
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin
Gene Symbols:
TG
Immunogen:
Human thyroid follicular cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Antigen: Thyroglobulin
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Gene Alias: AITD3TGN, TDH3, Tg, thyroglobulin
Host Species: Mouse
Molecular Weight of Antigen: 660 kDa
Quantity: 0.1 mL
Research Discipline: Cancer, Cell Biology
Gene ID (Entrez): 7038
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: TGB04 + TGB05
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin
Gene Symbols: TG
Immunogen: Human thyroid follicular cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen:
Thyroglobulin
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Gene Alias:
AITD3TGN, TDH3, Tg, thyroglobulin
Host Species:
Mouse
Molecular Weight of Antigen:
660 kDa
Quantity:
0.1 mL
Research Discipline:
Cancer, Cell Biology
Gene ID (Entrez):
7038
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
TGB04 + TGB05
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin
Gene Symbols:
TG
Immunogen:
Human thyroid follicular cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Antigen: Thyroglobulin
Classification: Monoclonal
Conjugate: Alexa Fluor 700
Gene Alias: AITD3TGN, TDH3, Tg, thyroglobulin
Host Species: Mouse
Molecular Weight of Antigen: 660 kDa
Quantity: 0.1 mL
Research Discipline: Cancer, Cell Biology
Gene ID (Entrez): 7038
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: TGB04 + TGB05
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin
Gene Symbols: TG
Immunogen: Human thyroid follicular cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen:
Thyroglobulin
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Gene Alias:
AITD3TGN, TDH3, Tg, thyroglobulin
Host Species:
Mouse
Molecular Weight of Antigen:
660 kDa
Quantity:
0.1 mL
Research Discipline:
Cancer, Cell Biology
Gene ID (Entrez):
7038
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
TGB04 + TGB05
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin
Gene Symbols:
TG
Immunogen:
Human thyroid follicular cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable m
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Antigen: Thymidylate Synthase
Classification: Monoclonal
Conjugate: DyLight 650
Gene Alias: EC 2.1.1.45, HsT422, MGC88736, thymidylate synthase, thymidylate synthetase, TMSTsase, TSase, TSHST422
Host Species: Mouse
Molecular Weight of Antigen: 36 kDa
Quantity: 0.1 mL
Research Discipline: Cancer, Cell Cycle and Replication, DNA Repair, DNA replication Transcription Translation and Splicing, Transcription Factors and Regulators, Translation Control
Gene ID (Entrez): 7298
Target Species: Human
Form: Purified
Applications: Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: TMS715
Dilution: Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols: TYMS
Immunogen: Recombinant full-length human Thymidylate Synthase protein. (Uniprot: P04818 )
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: It recognizes a protein of 36kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Antigen:
Thymidylate Synthase
Classification:
Monoclonal
Conjugate:
DyLight 650
Gene Alias:
EC 2.1.1.45, HsT422, MGC88736, thymidylate synthase, thymidylate synthetase, TMSTsase, TSase, TSHST422
Host Species:
Mouse
Molecular Weight of Antigen:
36 kDa
Quantity:
0.1 mL
Research Discipline:
Cancer, Cell Cycle and Replication, DNA Repair, DNA replication Transcription Translation and Splicing, Transcription Factors and Regulators, Translation Control
Gene ID (Entrez):
7298
Target Species:
Human
Form:
Purified
Applications:
Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
TMS715
Dilution:
Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Symbols:
TYMS
Immunogen:
Recombinant full-length human Thymidylate Synthase protein. (Uniprot: P04818 )
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
It recognizes a protein of 36kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ