NBP234795X

Chromogranin A Antibody (SPM553), Alexa Fluor™ 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP234795X-Each-of-1 In Stock ₹ 56,298.48

NBP234795X - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

Chromogranin A

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Gene Alias

betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Applications

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

SPM553

Dilution

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols

CHGA

Immunogen

Recombinant human chromogranin A protein (Uniprot: P10645)

Quantity

0.1 mL

Research Discipline

Apoptosis, Cancer, Neuronal Cell Markers

Gene ID (Entrez)

1113

Target Species

Human

Form

Purified

Description

  • Chromogranin A Monoclonal specifically detects Chromogranin A in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

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Novus Biologicals

NBP234795X

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Antigen:
Chromogranin A

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene Alias:
betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM553

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
CHGA

Immunogen:
Recombinant human chromogranin A protein (Uniprot: P10645)

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Neuronal Cell Markers

Gene ID (Entrez):
1113

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP234795Z

--


Antigen:
Chromogranin A

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Gene Alias:
betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM553

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
CHGA

Immunogen:
Recombinant human chromogranin A protein (Uniprot: P10645)

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Neuronal Cell Markers

Gene ID (Entrez):
1113

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP234796H

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Antigen:
CD35

Classification:
Monoclonal

Conjugate:
HRP

Gene Alias:
complement component (3b/4b) receptor 1 (Knops blood group), KN

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This monoclonal antibody is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This monoclonal antibody is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This monoclonal antibody labels follicular dendritic cells and follicular dendritic cell sarcoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
SPM554

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
CR1

Immunogen:
Intact human monocytes

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
1378

Target Species:
Human, Primate, Baboon

Form:
Purified

Img

Novus Biologicals

NBP234796J

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Antigen:
CD35

Classification:
Monoclonal

Conjugate:
APC

Gene Alias:
complement component (3b/4b) receptor 1 (Knops blood group), KN

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This monoclonal antibody is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This monoclonal antibody is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This monoclonal antibody labels follicular dendritic cells and follicular dendritic cell sarcoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
SPM554

Dilution:
Flow Cytometry

Gene Symbols:
CR1

Immunogen:
Intact human monocytes

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
1378

Target Species:
Human, Primate, Baboon

Form:
Purified