NBP234808X

UCH-L1/PGP9.5 Antibody (SPM575), Alexa Fluor™ 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP234808X-Each-of-1 In Stock ₹ 55,271.76

NBP234808X - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

UCH-L1/PGP9.5

Classification

Monoclonal

Conjugate

Alexa Fluor 488

Gene Alias

EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Content And Storage

Store at 4C in the dark.

Isotype

IgG2a κ

Applications

Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone

SPM575

Dilution

Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols

UCHL1

Immunogen

UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)

Quantity

0.1 mL

Research Discipline

Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission

Gene ID (Entrez)

7345

Target Species

Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish

Form

Purified

Description

  • UCH-L1/PGP9.5 Monoclonal specifically detects UCH-L1/PGP9.5 in Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish samples
  • It is validated for Western Blot, Immunocytochemistry/Immunofluorescence.

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Novus Biologicals

NBP234808X

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Antigen:
UCH-L1/PGP9.5

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene Alias:
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a κ

Applications:
Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
SPM575

Dilution:
Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
UCHL1

Immunogen:
UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)

Quantity:
0.1 mL

Research Discipline:
Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission

Gene ID (Entrez):
7345

Target Species:
Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish

Form:
Purified

Img

Novus Biologicals

NBP234808Y

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Antigen:
UCH-L1/PGP9.5

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene Alias:
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2a κ

Applications:
Western Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
SPM575

Dilution:
Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Symbols:
UCHL1

Immunogen:
UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)

Quantity:
0.1 mL

Research Discipline:
Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission

Gene ID (Entrez):
7345

Target Species:
Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish

Form:
Purified

Img

Novus Biologicals

NBP234809FR

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Antigen:
Vimentin

Classification:
Monoclonal

Conjugate:
DyLight 680

Gene Alias:
FLJ36605, vimentin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM576

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
VIM

Immunogen:
Human vimentin recombinant protein (Uniprot: P08670)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cellular Markers, Cytoskeleton Markers, Growth and Development, Hypoxia, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers, Stem Cells

Gene ID (Entrez):
7431

Target Species:
Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse (Negative), Rat (Negative)

Form:
Purified

Img

Novus Biologicals

NBP234809G

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Antigen:
Vimentin

Classification:
Monoclonal

Conjugate:
DyLight 488

Gene Alias:
FLJ36605, vimentin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM576

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
VIM

Immunogen:
Human vimentin recombinant protein (Uniprot: P08670)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cellular Markers, Cytoskeleton Markers, Growth and Development, Hypoxia, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers, Stem Cells

Gene ID (Entrez):
7431

Target Species:
Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse (Negative), Rat (Negative)

Form:
Purified