NBP234811Y

MALT1 Antibody (SPM578), Alexa Fluor™ 647, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP234811Y-Each-of-1 In Stock ₹ 53,688.90

NBP234811Y - Each of 1

₹ 53,688.90

In Stock

Quantity

1

Base Price: ₹ 53,688.90

GST (18%): ₹ 9,664.002

Total Price: ₹ 63,352.902

Antigen

MALT1

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Gene Alias

caspase-like protein, DKFZp434L132, EC 3.4.22.-, MALT associated translocation, MALT lymphoma-associated translocation, MLT1, MLTMALT-lymphoma associated translocation, mucosa associated lymphoid tissue lymphoma translocation gene 1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, paracaspase

Host Species

Mouse

Molecular Weight of Antigen

93 kDa

Quantity

0.1 mL

Research Discipline

Apoptosis, Cancer, Tumor Suppressors

Gene ID (Entrez)

10892

Target Species

Human

Form

Purified

Applications

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

SPM578

Dilution

Western Blot, Flow Cytometry, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols

MALT1

Immunogen

Human MALT1 recombinant fragment (aa701-808) (Uniprot: Q9UDY8)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

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Description

  • MALT1 Monoclonal specifically detects MALT1 in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Show Difference

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Novus Biologicals

NBP234811Y

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Antigen:
MALT1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene Alias:
caspase-like protein, DKFZp434L132, EC 3.4.22.-, MALT associated translocation, MALT lymphoma-associated translocation, MLT1, MLTMALT-lymphoma associated translocation, mucosa associated lymphoid tissue lymphoma translocation gene 1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, paracaspase

Host Species:
Mouse

Molecular Weight of Antigen:
93 kDa

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Tumor Suppressors

Gene ID (Entrez):
10892

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM578

Dilution:
Western Blot, Flow Cytometry, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
MALT1

Immunogen:
Human MALT1 recombinant fragment (aa701-808) (Uniprot: Q9UDY8)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234811Z

--


Antigen:
MALT1

Classification:
Monoclonal

Conjugate:
Alexa Fluor 700

Gene Alias:
caspase-like protein, DKFZp434L132, EC 3.4.22.-, MALT associated translocation, MALT lymphoma-associated translocation, MLT1, MLTMALT-lymphoma associated translocation, mucosa associated lymphoid tissue lymphoma translocation gene 1, mucosa-associated lymphoid tissue lymphoma translocation protein 1, paracaspase

Host Species:
Mouse

Molecular Weight of Antigen:
93 kDa

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Tumor Suppressors

Gene ID (Entrez):
10892

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM578

Dilution:
Western Blot, Flow Cytometry, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
MALT1

Immunogen:
Human MALT1 recombinant fragment (aa701-808) (Uniprot: Q9UDY8)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234812FR

--


Antigen:
DOG1/TMEM16A

Classification:
Monoclonal

Conjugate:
DyLight 680

Gene Alias:
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A

Host Species:
Mouse

Molecular Weight of Antigen:
114 kDa

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
55107

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM580

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
ANO1

Immunogen:
Recombinant human canine1/TMEM16A protein (Uniprot: Q5XX6)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP234812G

--


Antigen:
DOG1/TMEM16A

Classification:
Monoclonal

Conjugate:
DyLight 488

Gene Alias:
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A

Host Species:
Mouse

Molecular Weight of Antigen:
114 kDa

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
55107

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM580

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
ANO1

Immunogen:
Recombinant human canine1/TMEM16A protein (Uniprot: Q5XX6)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ