NBP234812W

DOG1/TMEM16A Antibody (SPM580), Alexa Fluor™ 405, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP234812W-Each-of-1 In Stock ₹ 55,271.76

NBP234812W - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

DOG1/TMEM16A

Classification

Monoclonal

Conjugate

Alexa Fluor 405

Gene Alias

ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A

Host Species

Mouse

Molecular Weight of Antigen

114 kDa

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.

Content And Storage

Store at 4C in the dark.

Isotype

IgG1 κ

Applications

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

SPM580

Dilution

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols

ANO1

Immunogen

Recombinant human canine1/TMEM16A protein (Uniprot: Q5XX6)

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

55107

Target Species

Human

Form

Purified

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Description

  • DOG1/TMEM16A Monoclonal specifically detects DOG1/TMEM16A in Human samples
  • It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

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Show Difference

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Novus Biologicals

NBP234812W

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Antigen:
DOG1/TMEM16A

Classification:
Monoclonal

Conjugate:
Alexa Fluor 405

Gene Alias:
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A

Host Species:
Mouse

Molecular Weight of Antigen:
114 kDa

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM580

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
ANO1

Immunogen:
Recombinant human canine1/TMEM16A protein (Uniprot: Q5XX6)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
55107

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP234812X

--


Antigen:
DOG1/TMEM16A

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Gene Alias:
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A

Host Species:
Mouse

Molecular Weight of Antigen:
114 kDa

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM580

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
ANO1

Immunogen:
Recombinant human canine1/TMEM16A protein (Uniprot: Q5XX6)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
55107

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP234812Y

--


Antigen:
DOG1/TMEM16A

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Gene Alias:
ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A

Host Species:
Mouse

Molecular Weight of Antigen:
114 kDa

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
SPM580

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Symbols:
ANO1

Immunogen:
Recombinant human canine1/TMEM16A protein (Uniprot: Q5XX6)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
55107

Target Species:
Human

Form:
Purified

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NBP234813FR

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Antigen:
Golgi Complex

Classification:
Monoclonal

Conjugate:
DyLight 680

Gene Alias:
__

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes Golgi complex in human cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. It recognizes an antigen associated with the Golgi complex in human cells only. It can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells and may be used to stain Golgi complex of cells in frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations. This monoclonal antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
SPM581

Dilution:
Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Symbols:
__

Immunogen:
SU-DHL-1 large cell lymphoma cells.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified