NBP24444101

AMPD3 Antibody (AMPD3/901), Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP24444101-Each-of-1 In Stock ₹ 43,336.14

NBP24444101 - Each of 1

₹ 43,336.14

In Stock

Quantity

1

Base Price: ₹ 43,336.14

GST (18%): ₹ 7,800.505

Total Price: ₹ 51,136.645

Antigen

AMPD3

Classification

Monoclonal

Concentration

0.2mg/mL

Dilution

Flow Cytometry 1 - 2 ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml, Immunocytochemistry 1 - 2.0 ug/ml

Gene Accession No.

Q01432

Gene Symbols

AMPD3

Immunogen

Recombinant full-length human AMDP3 protein

Quantity

0.1 mg

Primary or Secondary

Primary

Test Specificity

It recognizes a protein of ∼90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Content And Storage

Store at 4C.

Isotype

IgG2b κ

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry

Clone

AMPD3/901

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

adenosine monophosphate deaminase (isoform E), adenosine monophosphate deaminase 3, AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, EC 3.5.4.6, Erythrocyte AMP deaminase, erythrocyte type AMP deaminase, erythrocyte-specific AMP deaminase, myoadenylate deaminase

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

272

Target Species

Human

Form

Purified

Description

  • Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence AMPD3 Monoclonal specifically detects AMPD3 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Fischer Scientific

NBP24444101

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Antigen:
AMPD3

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 1 - 2 ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml, Immunocytochemistry 1 - 2.0 ug/ml

Gene Accession No.:
Q01432

Gene Symbols:
AMPD3

Immunogen:
Recombinant full-length human AMDP3 protein

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
It recognizes a protein of ∼90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry

Clone:
AMPD3/901

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
adenosine monophosphate deaminase (isoform E), adenosine monophosphate deaminase 3, AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, EC 3.5.4.6, Erythrocyte AMP deaminase, erythrocyte type AMP deaminase, erythrocyte-specific AMP deaminase, myoadenylate deaminase

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
272

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24444102

--


Antigen:
AMPD3

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 1 - 2 ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml, Immunocytochemistry 1 - 2.0 ug/ml

Gene Accession No.:
Q01432

Gene Symbols:
AMPD3

Immunogen:
Recombinant full-length human AMDP3 protein

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
It recognizes a protein of ∼90kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry

Clone:
AMPD3/901

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
adenosine monophosphate deaminase (isoform E), adenosine monophosphate deaminase 3, AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, EC 3.5.4.6, Erythrocyte AMP deaminase, erythrocyte type AMP deaminase, erythrocyte-specific AMP deaminase, myoadenylate deaminase

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
272

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24444500

--


Antigen:
Cytochrome c

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
__

Gene Symbols:
CYCS

Immunogen:
Recombinant cytochrome c protein

Quantity:
0.02 mg

Primary or Secondary:
Primary

Test Specificity:
Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
CTC05

Conjugate:
Unconjugated

Formulation:
1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
CYCHCS, cytochrome c, cytochrome c, somatic, THC4

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
54205

Target Species:
Human, Mouse, Rat, Amphibian, Avian, Canine, Drosophila, Equine

Form:
Purified

Img

Fischer Scientific

NBP24444501

--


Antigen:
Cytochrome c

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
__

Gene Symbols:
CYCS

Immunogen:
Recombinant cytochrome c protein

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
CTC05

Conjugate:
Unconjugated

Formulation:
1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
CYCHCS, cytochrome c, cytochrome c, somatic, THC4

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
54205

Target Species:
Human, Mouse, Rat, Amphibian, Avian, Canine, Drosophila, Equine

Form:
Purified