NBP24455201

CPS1 Antibody (SPM615), Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP24455201-Each-of-1 In Stock ₹ 43,336.14

NBP24455201 - Each of 1

₹ 43,336.14

In Stock

Quantity

1

Base Price: ₹ 43,336.14

GST (18%): ₹ 7,800.505

Total Price: ₹ 51,136.645

Antigen

CPS1

Classification

Monoclonal

Concentration

0.2mg/mL

Dilution

Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.

P31327

Gene Symbols

CPS1

Immunogen

Recombinant human CPS1 protein

Quantity

0.1 mg

Primary or Secondary

Primary

Test Specificity

This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

Content And Storage

Store at 4C.

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Immunofluorescence

Clone

SPM615

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

1373

Target Species

Human, Canine

Form

Purified

Description

  • Ensure accurate, reproducible results in Immunohistochemistry (Paraffin), Immunofluorescence CPS1 Monoclonal specifically detects CPS1 in Human, Canine samples
  • It is validated for Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Compare Similar Items

Show Difference

Img

Fischer Scientific

NBP24455201

--


Antigen:
CPS1

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
P31327

Gene Symbols:
CPS1

Immunogen:
Recombinant human CPS1 protein

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

Content And Storage:
Store at 4C.

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SPM615

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
1373

Target Species:
Human, Canine

Form:
Purified

Img

Fischer Scientific

NBP24455202

--


Antigen:
CPS1

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
P31327

Gene Symbols:
CPS1

Immunogen:
Recombinant human CPS1 protein

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

Content And Storage:
Store at 4C.

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SPM615

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
1373

Target Species:
Human, Canine

Form:
Purified

Img

Fischer Scientific

NBP24455600

--


Antigen:
CD6

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
__

Gene Symbols:
CD6

Immunogen:
CD8+ cytotoxic T-cell clone

Quantity:
0.02 mg

Primary or Secondary:
Primary

Test Specificity:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Content And Storage:
Store at 4C.

Isotype:
IgG1

Applications:
Flow Cytometry, SDS-Page, Immunofluorescence

Clone:
SPV-L14

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
CD6 antigenFLJ44171, CD6 molecule, T12, Tp120, TP120T-cell differentiation antigen CD6

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
923

Target Species:
Human, Mouse

Form:
Purified

Img

Fischer Scientific

NBP24455601

--


Antigen:
CD6

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
__

Gene Symbols:
CD6

Immunogen:
CD8+ cytotoxic T-cell clone

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Content And Storage:
Store at 4C.

Isotype:
IgG1

Applications:
Flow Cytometry, SDS-Page, Immunofluorescence

Clone:
SPV-L14

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
CD6 antigenFLJ44171, CD6 molecule, T12, Tp120, TP120T-cell differentiation antigen CD6

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
923

Target Species:
Human, Mouse

Form:
Purified