NBP24455602
CD6 Antibody (SPV-L14), Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
CD6
Classification
Monoclonal
Concentration
0.2 mg/mL
Dilution
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias
CD6 antigenFLJ44171, CD6 molecule, T12, Tp120, TP120T-cell differentiation antigen CD6
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Content And Storage
Store at 4C.
Isotype
IgG1
Applications
Flow Cytometry, SDS-Page, Immunofluorescence
Clone
SPV-L14
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
CD6
Immunogen
CD8+ cytotoxic T-cell clone
Quantity
0.2 mg
Research Discipline
Immunology
Gene ID (Entrez)
923
Target Species
Human, Mouse
Form
Purified
Description
- Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence CD6 Monoclonal specifically detects CD6 in Human, Mouse samples
- It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.
Compare Similar Items
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Antigen: CD6
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias: CD6 antigenFLJ44171, CD6 molecule, T12, Tp120, TP120T-cell differentiation antigen CD6
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Content And Storage: Store at 4C.
Isotype: IgG1
Applications: Flow Cytometry, SDS-Page, Immunofluorescence
Clone: SPV-L14
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CD6
Immunogen: CD8+ cytotoxic T-cell clone
Quantity: 0.2 mg
Research Discipline: Immunology
Gene ID (Entrez): 923
Target Species: Human, Mouse
Form: Purified
Antigen:
CD6
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias:
CD6 antigenFLJ44171, CD6 molecule, T12, Tp120, TP120T-cell differentiation antigen CD6
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Content And Storage:
Store at 4C.
Isotype:
IgG1
Applications:
Flow Cytometry, SDS-Page, Immunofluorescence
Clone:
SPV-L14
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CD6
Immunogen:
CD8+ cytotoxic T-cell clone
Quantity:
0.2 mg
Research Discipline:
Immunology
Gene ID (Entrez):
923
Target Species:
Human, Mouse
Form:
Purified
Antigen: CD30/TNFRSF8
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry, Immunohistochemistry-Paraffin 1:50 - 1:100, Immunofluorescence 1:50 - 1:100
Gene Alias: CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Host Species: Mouse
Purification Method: Tissue culture supernatant
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: Ber-H2
Conjugate: Unconjugated
Formulation: No buffer with 0.05% Sodium Azide
Gene Symbols: TNFRSF8
Immunogen: Co cell line established from a patient with Hodgkin s disease of T-cell lineage
Quantity: 0.1 mL
Research Discipline: Apoptosis, Cell Cycle and Replication, Embryonic Stem Cell Markers, Immunology, Stem Cell Markers
Gene ID (Entrez): 943
Target Species: Human
Form: Supernatant
Antigen:
CD30/TNFRSF8
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry, Immunohistochemistry-Paraffin 1:50 - 1:100, Immunofluorescence 1:50 - 1:100
Gene Alias:
CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Host Species:
Mouse
Purification Method:
Tissue culture supernatant
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
Ber-H2
Conjugate:
Unconjugated
Formulation:
No buffer with 0.05% Sodium Azide
Gene Symbols:
TNFRSF8
Immunogen:
Co cell line established from a patient with Hodgkin s disease of T-cell lineage
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Cell Cycle and Replication, Embryonic Stem Cell Markers, Immunology, Stem Cell Markers
Gene ID (Entrez):
943
Target Species:
Human
Form:
Supernatant
Antigen: CD30/TNFRSF8
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry, Immunohistochemistry-Paraffin 1:50 - 1:100, Immunofluorescence 1:50 - 1:100
Gene Alias: CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Host Species: Mouse
Purification Method: Tissue culture supernatant
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: Ber-H2
Conjugate: Unconjugated
Formulation: No buffer with 0.05% Sodium Azide
Gene Symbols: TNFRSF8
Immunogen: Co cell line established from a patient with Hodgkin s disease of T-cell lineage
Quantity: 0.5 mL
Research Discipline: Apoptosis, Cell Cycle and Replication, Embryonic Stem Cell Markers, Immunology, Stem Cell Markers
Gene ID (Entrez): 943
Target Species: Human
Form: Supernatant
Antigen:
CD30/TNFRSF8
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry, Immunohistochemistry-Paraffin 1:50 - 1:100, Immunofluorescence 1:50 - 1:100
Gene Alias:
CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Host Species:
Mouse
Purification Method:
Tissue culture supernatant
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
Ber-H2
Conjugate:
Unconjugated
Formulation:
No buffer with 0.05% Sodium Azide
Gene Symbols:
TNFRSF8
Immunogen:
Co cell line established from a patient with Hodgkin s disease of T-cell lineage
Quantity:
0.5 mL
Research Discipline:
Apoptosis, Cell Cycle and Replication, Embryonic Stem Cell Markers, Immunology, Stem Cell Markers
Gene ID (Entrez):
943
Target Species:
Human
Form:
Supernatant
Antigen: CD30/TNFRSF8
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml
Gene Alias: CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkins disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone: Ki-1/779
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: TNFRSF8
Immunogen: Recombinant human TNFRSF8 protein
Quantity: 0.02 mg
Research Discipline: Apoptosis, Cell Cycle and Replication, Embryonic Stem Cell Markers, Immunology, Stem Cell Markers
Gene ID (Entrez): 943
Target Species: Human
Form: Purified
Antigen:
CD30/TNFRSF8
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml
Gene Alias:
CD30, CD30 antigen, CD30KI-1, CD30L receptor, cytokine receptor CD30, D1S166EKi-1, Ki-1 antigen, Lymphocyte activation antigen CD30, tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkins disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone:
Ki-1/779
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
TNFRSF8
Immunogen:
Recombinant human TNFRSF8 protein
Quantity:
0.02 mg
Research Discipline:
Apoptosis, Cell Cycle and Replication, Embryonic Stem Cell Markers, Immunology, Stem Cell Markers
Gene ID (Entrez):
943
Target Species:
Human
Form:
Purified