NBP24475202
Laminin gamma 1 Antibody (SPM193), Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
Laminin gamma 1
Classification
Monoclonal
Concentration
0.2mg/mL
Dilution
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Gene Alias
LAMB2Laminin-7 subunit gamma, Laminin B2 chain, laminin subunit gamma-1, laminin, gamma 1 (formerly LAMB2), Laminin-1 subunit gamma, Laminin-10 subunit gamma, Laminin-11 subunit gamma, Laminin-2 subunit gamma, Laminin-3 subunit gamma, Laminin-4 subunit gamma, Laminin-6 subunit gamma, Laminin-8 subunit gamma, Laminin-9 subunit gamma, MGC87297, S-LAM gamma, S-laminin subunit gamma
Host Species
Rat
Molecular Weight of Antigen
210 kDa
Quantity
0.2 mg
Research Discipline
Apoptosis, Cancer, Cytoskeleton Markers, Extracellular Matrix, Tumor Suppressors
Gene ID (Entrez)
3915
Target Species
Human, Mouse
Form
Purified
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone
SPM193
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
LAMC1
Immunogen
Murine EHS laminin preparation
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. This MAb reacts with laminin B2/1 chain of ∼210kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types
Content And Storage
Store at 4C.
Isotype
IgG2a κ
Description
- Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence Laminin gamma 1 Monoclonal specifically detects Laminin gamma 1 in Human, Mouse samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.
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Antigen: Laminin gamma 1
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Gene Alias: LAMB2Laminin-7 subunit gamma, Laminin B2 chain, laminin subunit gamma-1, laminin, gamma 1 (formerly LAMB2), Laminin-1 subunit gamma, Laminin-10 subunit gamma, Laminin-11 subunit gamma, Laminin-2 subunit gamma, Laminin-3 subunit gamma, Laminin-4 subunit gamma, Laminin-6 subunit gamma, Laminin-8 subunit gamma, Laminin-9 subunit gamma, MGC87297, S-LAM gamma, S-laminin subunit gamma
Host Species: Rat
Molecular Weight of Antigen: 210 kDa
Quantity: 0.2 mg
Research Discipline: Apoptosis, Cancer, Cytoskeleton Markers, Extracellular Matrix, Tumor Suppressors
Gene ID (Entrez): 3915
Target Species: Human, Mouse
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: SPM193
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: LAMC1
Immunogen: Murine EHS laminin preparation
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. This MAb reacts with laminin B2/1 chain of ∼210kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Antigen:
Laminin gamma 1
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Gene Alias:
LAMB2Laminin-7 subunit gamma, Laminin B2 chain, laminin subunit gamma-1, laminin, gamma 1 (formerly LAMB2), Laminin-1 subunit gamma, Laminin-10 subunit gamma, Laminin-11 subunit gamma, Laminin-2 subunit gamma, Laminin-3 subunit gamma, Laminin-4 subunit gamma, Laminin-6 subunit gamma, Laminin-8 subunit gamma, Laminin-9 subunit gamma, MGC87297, S-LAM gamma, S-laminin subunit gamma
Host Species:
Rat
Molecular Weight of Antigen:
210 kDa
Quantity:
0.2 mg
Research Discipline:
Apoptosis, Cancer, Cytoskeleton Markers, Extracellular Matrix, Tumor Suppressors
Gene ID (Entrez):
3915
Target Species:
Human, Mouse
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
SPM193
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
LAMC1
Immunogen:
Murine EHS laminin preparation
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of alpha, beta, and gamma chains. This MAb reacts with laminin B2/1 chain of ∼210kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Antigen: CD8 beta
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias: CD8 antigen, beta polypeptide 1 (p37), CD8b antigen, CD8b molecule, CD8B1P37, LEU2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T-cell surface glycoprotein CD8 beta chain
Host Species: Mouse
Molecular Weight of Antigen: 32 kDa
Quantity: 0.02 mg
Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 926
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunofluorescence
Clone: BU88
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CD8B
Immunogen: Human CD8 beta
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The T cell receptor (TCR) is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (alpha-alpha or alpha-beta) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
CD8 beta
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias:
CD8 antigen, beta polypeptide 1 (p37), CD8b antigen, CD8b molecule, CD8B1P37, LEU2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T-cell surface glycoprotein CD8 beta chain
Host Species:
Mouse
Molecular Weight of Antigen:
32 kDa
Quantity:
0.02 mg
Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
926
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunofluorescence
Clone:
BU88
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CD8B
Immunogen:
Human CD8 beta
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The T cell receptor (TCR) is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (alpha-alpha or alpha-beta) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: CD8 beta
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias: CD8 antigen, beta polypeptide 1 (p37), CD8b antigen, CD8b molecule, CD8B1P37, LEU2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T-cell surface glycoprotein CD8 beta chain
Host Species: Mouse
Molecular Weight of Antigen: 32 kDa
Quantity: 0.1 mg
Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 926
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunofluorescence
Clone: BU88
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CD8B
Immunogen: Human CD8 beta
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The T cell receptor (TCR) is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (alpha-alpha or alpha-beta) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
CD8 beta
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias:
CD8 antigen, beta polypeptide 1 (p37), CD8b antigen, CD8b molecule, CD8B1P37, LEU2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T-cell surface glycoprotein CD8 beta chain
Host Species:
Mouse
Molecular Weight of Antigen:
32 kDa
Quantity:
0.1 mg
Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
926
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunofluorescence
Clone:
BU88
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CD8B
Immunogen:
Human CD8 beta
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The T cell receptor (TCR) is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (alpha-alpha or alpha-beta) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: CD8 beta
Classification: Monoclonal
Concentration: 0.2 mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias: CD8 antigen, beta polypeptide 1 (p37), CD8b antigen, CD8b molecule, CD8B1P37, LEU2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T-cell surface glycoprotein CD8 beta chain
Host Species: Mouse
Molecular Weight of Antigen: 32 kDa
Quantity: 0.2 mg
Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 926
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunofluorescence
Clone: BU88
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CD8B
Immunogen: Human CD8 beta
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The T cell receptor (TCR) is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (alpha-alpha or alpha-beta) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
CD8 beta
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias:
CD8 antigen, beta polypeptide 1 (p37), CD8b antigen, CD8b molecule, CD8B1P37, LEU2, LY3, LYT3, MGC119115, T lymphocyte surface glycoprotein beta chain, T-cell surface glycoprotein CD8 beta chain
Host Species:
Mouse
Molecular Weight of Antigen:
32 kDa
Quantity:
0.2 mg
Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
926
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunofluorescence
Clone:
BU88
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CD8B
Immunogen:
Human CD8 beta
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The T cell receptor (TCR) is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (alpha-alpha or alpha-beta) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ