NBP24489302

NF-L Antibody (NFL/736), Novus Biologicals™

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

NF-L

Classification

Monoclonal

Concentration

0.2mg/mL

Dilution

Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.

P07196

Gene Symbols

NEFL

Immunogen

Recombinant human NEFL protein

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This MAb reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Content And Storage

Store at 4C.

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Immunofluorescence

Clone

NFL/736

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

68 kDa neurofilament protein, neurofilament protein, light chain, neurofilament subunit NF-L, Neurofilament triplet L protein, neurofilament, light polypeptide, neurofilament-light, NF68FLJ53642, NF-L, NFLlight polypeptide 68kDa

Host Species

Mouse

Molecular Weight of Antigen

68 kDa

Quantity

0.2 mg

Research Discipline

Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience

Gene ID (Entrez)

4747

Target Species

Human, Rat, Porcine, Chicken, Primate

Form

Purified

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Description

  • Ensure accurate, reproducible results in Immunohistochemistry (Paraffin), Immunofluorescence NF-L Monoclonal specifically detects NF-L in Human, Rat, Porcine, Bovine, Chicken samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

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Fischer Scientific

NBP24489302

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Antigen:
NF-L

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
P07196

Gene Symbols:
NEFL

Immunogen:
Recombinant human NEFL protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Content And Storage:
Store at 4C.

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
NFL/736

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
68 kDa neurofilament protein, neurofilament protein, light chain, neurofilament subunit NF-L, Neurofilament triplet L protein, neurofilament, light polypeptide, neurofilament-light, NF68FLJ53642, NF-L, NFLlight polypeptide 68kDa

Host Species:
Mouse

Molecular Weight of Antigen:
68 kDa

Quantity:
0.2 mg

Research Discipline:
Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience

Gene ID (Entrez):
4747

Target Species:
Human, Rat, Porcine, Chicken, Primate

Form:
Purified

Img

Fischer Scientific

NBP24489400

--


Antigen:
CEACAM5/CD66e

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
P06731

Gene Symbols:
CEACAM5

Immunogen:
Purified human CEA protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb reacts with nonspecific cross-reacting antigen (NCA). It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Clone:
C66/1260

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.02 mg

Research Discipline:
Cancer, Cellular Markers, Immunology

Gene ID (Entrez):
1048

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24489401

--


Antigen:
CEACAM5/CD66e

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
P06731

Gene Symbols:
CEACAM5

Immunogen:
Purified human CEA protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb reacts with nonspecific cross-reacting antigen (NCA). It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Clone:
C66/1260

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mg

Research Discipline:
Cancer, Cellular Markers, Immunology

Gene ID (Entrez):
1048

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24489402

--


Antigen:
CEACAM5/CD66e

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
P06731

Gene Symbols:
CEACAM5

Immunogen:
Purified human CEA protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb reacts with nonspecific cross-reacting antigen (NCA). It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Clone:
C66/1260

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.2 mg

Research Discipline:
Cancer, Cellular Markers, Immunology

Gene ID (Entrez):
1048

Target Species:
Human

Form:
Purified