NBP24496202

Alkaline Phosphatase, Tissue Non-Specific Antibody (V17.1), Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

Alkaline Phosphatase, Tissue Non-Specific

Classification

Monoclonal

Concentration

0.2 mg/mL

Dilution

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.

P05186, P05187

Gene Symbols

ALPL

Immunogen

Bovine intestinal alkaline phosphatase

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

249

Target Species

Human, Primate

Form

Purified

Applications

Flow Cytometry, Immunohistochemistry (Frozen), SDS-Page, Immunofluorescence

Clone

V17.1

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

Alkaline phosphatase liver/bone/kidney isozyme, alkaline phosphatase, liver/bone/kidney, alkaline phosphatase, tissue-nonspecific isozyme, alkaline phosphomonoesterase, APTNAP, AP-TNAP, EC 3.1.3.1, FLJ40094, FLJ93059, glycerophosphatase, HOPS, liver/bone/kidney-type alkaline phosphatase, MGC161443, tissue-nonspecific ALP, TNAP, TNSALPMGC167935

Host Species

Mouse

Molecular Weight of Antigen

55 kDa

Quantity

0.2 mg

Primary or Secondary

Primary

Test Specificity

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively sp

Content And Storage

Store at 4C.

Isotype

IgG1 κ

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Description

  • Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Frozen), Immunofluorescence Alkaline Phosphatase, Tissue Non-Specific Monoclonal specifically detects Alkaline Phosphatase, Tissue Non-Specific in Human, Bovine samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunofluorescence.

Compare Similar Items

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Fischer Scientific

NBP24496202

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Antigen:
Alkaline Phosphatase, Tissue Non-Specific

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
P05186, P05187

Gene Symbols:
ALPL

Immunogen:
Bovine intestinal alkaline phosphatase

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
249

Target Species:
Human, Primate

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), SDS-Page, Immunofluorescence

Clone:
V17.1

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Alkaline phosphatase liver/bone/kidney isozyme, alkaline phosphatase, liver/bone/kidney, alkaline phosphatase, tissue-nonspecific isozyme, alkaline phosphomonoesterase, APTNAP, AP-TNAP, EC 3.1.3.1, FLJ40094, FLJ93059, glycerophosphatase, HOPS, liver/bone/kidney-type alkaline phosphatase, MGC161443, tissue-nonspecific ALP, TNAP, TNSALPMGC167935

Host Species:
Mouse

Molecular Weight of Antigen:
55 kDa

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively sp

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

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NBP24496500

--


Antigen:
Arginase 1/ARG1/liver Arginase

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
P05089

Gene Symbols:
ARG1

Immunogen:
Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
383

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
ARG1/1125

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase

Host Species:
Mouse

Molecular Weight of Antigen:
36.5 kDa

Quantity:
0.02 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Content And Storage:
Store at 4C.

Isotype:
IgG3 κ

Img

Fischer Scientific

NBP24496501

--


Antigen:
Arginase 1/ARG1/liver Arginase

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
P05089

Gene Symbols:
ARG1

Immunogen:
Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
383

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
ARG1/1125

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase

Host Species:
Mouse

Molecular Weight of Antigen:
36.5 kDa

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Content And Storage:
Store at 4C.

Isotype:
IgG3 κ

Img

Fischer Scientific

NBP24496502

--


Antigen:
Arginase 1/ARG1/liver Arginase

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
P05089

Gene Symbols:
ARG1

Immunogen:
Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
383

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
ARG1/1125

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase

Host Species:
Mouse

Molecular Weight of Antigen:
36.5 kDa

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Content And Storage:
Store at 4C.

Isotype:
IgG3 κ