NBP24508702

Kappa Light Chain Antibody (Kap-56), Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

Kappa Light Chain

Classification

Monoclonal

Concentration

0.2mg/mL

Dilution

Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 2.0 ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml

Gene Alias

HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

Applications

Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone

Kap-56

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols

IGKC

Immunogen

Human lymphocytes stimulated

Quantity

0.2 mg

Research Discipline

Adaptive Immunity, Immunology

Gene ID (Entrez)

3514

Target Species

Human

Form

Purified

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Description

  • Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin) Kappa Light Chain Monoclonal specifically detects Kappa Light Chain in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Fischer Scientific

NBP24508702

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Antigen:
Kappa Light Chain

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 2.0 ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml

Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
Kap-56

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
IGKC

Immunogen:
Human lymphocytes stimulated

Quantity:
0.2 mg

Research Discipline:
Adaptive Immunity, Immunology

Gene ID (Entrez):
3514

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24509300

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Antigen:
IFN-alpha 2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Alias:
alpha-2a interferon, IFNA, IFN-alpha-2, IFN-alphaA, INFA2, interferon alpha 2b, interferon alpha A, interferon alpha-2, Interferon alpha-A, interferon, alpha 2, LeIF A, MGC125764, MGC125765

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I an

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, SDS-Page, Immunofluorescence

Clone:
N39

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
IFNA2

Immunogen:
Purified recombinant human IFN-alpha2

Quantity:
0.02 mg

Research Discipline:
Apoptosis, Cytokine Research

Gene ID (Entrez):
3440

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24509301

--


Antigen:
IFN-alpha 2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Alias:
alpha-2a interferon, IFNA, IFN-alpha-2, IFN-alphaA, INFA2, interferon alpha 2b, interferon alpha A, interferon alpha-2, Interferon alpha-A, interferon, alpha 2, LeIF A, MGC125764, MGC125765

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I an

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, SDS-Page, Immunofluorescence

Clone:
N39

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
IFNA2

Immunogen:
Purified recombinant human IFN-alpha2

Quantity:
0.1 mg

Research Discipline:
Apoptosis, Cytokine Research

Gene ID (Entrez):
3440

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24509302

--


Antigen:
IFN-alpha 2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Alias:
alpha-2a interferon, IFNA, IFN-alpha-2, IFN-alphaA, INFA2, interferon alpha 2b, interferon alpha A, interferon alpha-2, Interferon alpha-A, interferon, alpha 2, LeIF A, MGC125764, MGC125765

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I an

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, SDS-Page, Immunofluorescence

Clone:
N39

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
IFNA2

Immunogen:
Purified recombinant human IFN-alpha2

Quantity:
0.2 mg

Research Discipline:
Apoptosis, Cytokine Research

Gene ID (Entrez):
3440

Target Species:
Human

Form:
Purified