Manufacturer: Fischer Scientific
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Insulin
Monoclonal
0.2mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
P01308
INS
Recombinant INS protein
Protein A or G purified
RUO
Primary
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Store at 4C.
IgG1 κ
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
IRDN/805
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
Mouse
6 kDa
0.2 mg
Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers
3630
Human, Mouse, Porcine, Primate, Rabbit, Rat (Negative)
Purified