NBP24510902

Insulin Antibody (IRDN/805), Novus Biologicals™

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Insulin

Classification

Monoclonal

Concentration

0.2mg/mL

Dilution

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.

P01308

Gene Symbols

INS

Immunogen

Recombinant INS protein

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

IRDN/805

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

Host Species

Mouse

Molecular Weight of Antigen

6 kDa

Quantity

0.2 mg

Research Discipline

Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers

Gene ID (Entrez)

3630

Target Species

Human, Mouse, Porcine, Primate, Rabbit, Rat (Negative)

Form

Purified

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Description

  • Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence Insulin Monoclonal specifically detects Insulin in Human, Mouse, Porcine, Bovine, Rabbit, Rat (Negative) samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

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Fischer Scientific

NBP24510902

--


Antigen:
Insulin

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
P01308

Gene Symbols:
INS

Immunogen:
Recombinant INS protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
IRDN/805

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin

Host Species:
Mouse

Molecular Weight of Antigen:
6 kDa

Quantity:
0.2 mg

Research Discipline:
Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers

Gene ID (Entrez):
3630

Target Species:
Human, Mouse, Porcine, Primate, Rabbit, Rat (Negative)

Form:
Purified

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NBP24511200

--


Antigen:
PTH

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
__

Gene Symbols:
PTH

Immunogen:
A synthetic peptide from the N-terminal of human PTH polypeptide.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SPM604

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1

Host Species:
Mouse

Molecular Weight of Antigen:
9 kDa

Quantity:
0.02 mg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
5741

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24511201

--


Antigen:
PTH

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
__

Gene Symbols:
PTH

Immunogen:
A synthetic peptide from the N-terminal of human PTH polypeptide.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SPM604

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1

Host Species:
Mouse

Molecular Weight of Antigen:
9 kDa

Quantity:
0.1 mg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
5741

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24511202

--


Antigen:
PTH

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml

Gene Accession No.:
__

Gene Symbols:
PTH

Immunogen:
A synthetic peptide from the N-terminal of human PTH polypeptide.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SPM604

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1

Host Species:
Mouse

Molecular Weight of Antigen:
9 kDa

Quantity:
0.2 mg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
5741

Target Species:
Human

Form:
Purified