NBP24523702

Carbonic Anhydrase IX/CA9 Antibody (CA9/781), Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

Carbonic Anhydrase IX/CA9

Classification

Monoclonal

Concentration

0.2mg/mL

Dilution

Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.

Q16790

Gene Symbols

CA9

Immunogen

Recombinant human CA9 protein

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a glycoprotein of ∼200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Carbonic Anhydrases (CAs) are members of a large family of zinc metallo-enzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA IX is specifically expressed in clear-cell renal carcinomas.

Content And Storage

Store at 4C.

Isotype

IgG2b κ

Applications

Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Clone

CA9/781

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

CA-IX, CAIXcarbonic anhydrase 9, Carbonate dehydratase IX, carbonic anhydrase IXpMW1, carbonic dehydratase, EC 4.2.1.1, G250, Membrane antigen MN, MNRCC-associated antigen G250, P54/58N, RCC-associated protein G250, Renal cell carcinoma-associated antigen G250

Host Species

Mouse

Molecular Weight of Antigen

55 kDa

Quantity

0.2 mg

Research Discipline

Cancer, Cellular Markers, HIF Target Genes, Hypoxia, Lipid and Metabolism, Signal Transduction, Vision

Gene ID (Entrez)

768

Target Species

Human, Equine

Form

Purified

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Description

  • Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence Carbonic Anhydrase IX/CA9 Monoclonal specifically detects Carbonic Anhydrase IX/CA9 in Human, Equine samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Fischer Scientific

NBP24523702

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Antigen:
Carbonic Anhydrase IX/CA9

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
Q16790

Gene Symbols:
CA9

Immunogen:
Recombinant human CA9 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a glycoprotein of ∼200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Carbonic Anhydrases (CAs) are members of a large family of zinc metallo-enzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA IX is specifically expressed in clear-cell renal carcinomas.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Clone:
CA9/781

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
CA-IX, CAIXcarbonic anhydrase 9, Carbonate dehydratase IX, carbonic anhydrase IXpMW1, carbonic dehydratase, EC 4.2.1.1, G250, Membrane antigen MN, MNRCC-associated antigen G250, P54/58N, RCC-associated protein G250, Renal cell carcinoma-associated antigen G250

Host Species:
Mouse

Molecular Weight of Antigen:
55 kDa

Quantity:
0.2 mg

Research Discipline:
Cancer, Cellular Markers, HIF Target Genes, Hypoxia, Lipid and Metabolism, Signal Transduction, Vision

Gene ID (Entrez):
768

Target Species:
Human, Equine

Form:
Purified

Img

Fischer Scientific

NBP24524400

--


Antigen:
Napsin A

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
O96009

Gene Symbols:
NAPSA

Immunogen:
Recombinant fragment of human Napsin-A protein

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Content And Storage:
Store at 4C.

Isotype:
IgG κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Clone:
NAPSA/1238

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Asp 4, ASP4, Aspartyl protease 4, EC 3.4.23, EC 3.4.23.-, EC 3.4.23.15, EC 3.4.23.3, EC 3.4.23.5, KAP, Kdap, NAP1napsin-A, NAPApronapsin A, NAPSA, napsin A aspartic peptidase, napsin-1, SNAPA, TA01/TA02

Host Species:
Mouse

Molecular Weight of Antigen:
37 kDa

Quantity:
0.02 mg

Research Discipline:
Cancer, Cell Biology, Cellular Markers

Gene ID (Entrez):
9476

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24524401

--


Antigen:
Napsin A

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
O96009

Gene Symbols:
NAPSA

Immunogen:
Recombinant fragment of human Napsin-A protein

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Content And Storage:
Store at 4C.

Isotype:
IgG κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Clone:
NAPSA/1238

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Asp 4, ASP4, Aspartyl protease 4, EC 3.4.23, EC 3.4.23.-, EC 3.4.23.15, EC 3.4.23.3, EC 3.4.23.5, KAP, Kdap, NAP1napsin-A, NAPApronapsin A, NAPSA, napsin A aspartic peptidase, napsin-1, SNAPA, TA01/TA02

Host Species:
Mouse

Molecular Weight of Antigen:
37 kDa

Quantity:
0.1 mg

Research Discipline:
Cancer, Cell Biology, Cellular Markers

Gene ID (Entrez):
9476

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP24524402

--


Antigen:
Napsin A

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.:
O96009

Gene Symbols:
NAPSA

Immunogen:
Recombinant fragment of human Napsin-A protein

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Content And Storage:
Store at 4C.

Isotype:
IgG κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Clone:
NAPSA/1238

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias:
Asp 4, ASP4, Aspartyl protease 4, EC 3.4.23, EC 3.4.23.-, EC 3.4.23.15, EC 3.4.23.3, EC 3.4.23.5, KAP, Kdap, NAP1napsin-A, NAPApronapsin A, NAPSA, napsin A aspartic peptidase, napsin-1, SNAPA, TA01/TA02

Host Species:
Mouse

Molecular Weight of Antigen:
37 kDa

Quantity:
0.2 mg

Research Discipline:
Cancer, Cell Biology, Cellular Markers

Gene ID (Entrez):
9476

Target Species:
Human

Form:
Purified