Manufacturer: Fischer Scientific
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IgM Heavy Chain
Monoclonal
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Mouse
Protein A or G purified
RUO
3507
Human
Purified
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
IM260 + IM373 + ICO-30
Western Blot 0.5 - 1 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1ml, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1 ug/ml
IGHM
Recombinant heavy chain of human IgM (IM260 & IM373); Heavy chain of human IgM (ICO-30)
0.2 mg
Primary
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Store at 4C.
IgG1, IgG2b κ