NBP247670FR

HLA-DR Antibody (LN-3), DyLight 680, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP247670FR-Each-of-1 In Stock ₹ 54,245.04

NBP247670FR - Each of 1

₹ 54,245.04

In Stock

Quantity

1

Base Price: ₹ 54,245.04

GST (18%): ₹ 9,764.107

Total Price: ₹ 64,009.147

Antigen

HLA-DR

Classification

Monoclonal

Conjugate

DyLight 680

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

HLA-DRA

Immunogen

Activated human peripheral blood mononuclear cells

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvir

Content And Storage

Store at 4C in the dark.

Isotype

IgG2b κ

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

LN-3

Dilution

Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias

FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes

Gene ID (Entrez)

3122

Target Species

Human, Monkey, Mouse (Negative)

Form

Purified

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Description

  • HLA-DR Monoclonal specifically detects HLA-DR in Human, Monkey, Mouse (Negative) samples
  • It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP247670FR

--


Antigen:
HLA-DR

Classification:
Monoclonal

Conjugate:
DyLight 680

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
HLA-DRA

Immunogen:
Activated human peripheral blood mononuclear cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvir

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
LN-3

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes

Gene ID (Entrez):
3122

Target Species:
Human, Monkey, Mouse (Negative)

Form:
Purified

Img

Novus Biologicals

NBP247670H

--


Antigen:
HLA-DR

Classification:
Monoclonal

Conjugate:
HRP

Formulation:
PBS with No Preservative

Gene Symbols:
HLA-DRA

Immunogen:
Activated human peripheral blood mononuclear cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvir

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
LN-3

Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes

Gene ID (Entrez):
3122

Target Species:
Human, Monkey, Mouse (Negative)

Form:
Purified

Img

Novus Biologicals

NBP247670IR

--


Antigen:
HLA-DR

Classification:
Monoclonal

Conjugate:
DyLight 755

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
HLA-DRA

Immunogen:
Activated human peripheral blood mononuclear cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvir

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
LN-3

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes

Gene ID (Entrez):
3122

Target Species:
Human, Monkey, Mouse (Negative)

Form:
Purified

Img

Novus Biologicals

NBP247670PE

--


Antigen:
HLA-DR

Classification:
Monoclonal

Conjugate:
PE

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
HLA-DRA

Immunogen:
Activated human peripheral blood mononuclear cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 28kDa chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each others respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG2b κ

Applications:
Flow Cytometry

Clone:
LN-3

Dilution:
Flow Cytometry

Gene Alias:
FLJ51114, histocompatibility antigen HLA-DR alpha, HLA class II histocompatibility antigen, DR alpha chain, HLA-DRA1, major histocompatibility complex, class II, DR alpha, MHC cell surface glycoprotein, MHC class II antigen DRA, MLRW

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Biology, Cellular Markers, Diabetes Research, Immunology, Major Histocompatibility Complexes

Gene ID (Entrez):
3122

Target Species:
Human, Monkey, Mouse (Negative)

Form:
Purified