NBP247743A

EGFR Antibody (31G7 + GFR1195) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP247743A-Each-of-1 In Stock ₹ 56,298.48

NBP247743A - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

EGFR

Classification

Monoclonal

Concentration

1.0 mg/mL

Dilution

Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 2 - 4 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Gene Alias

avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone

31G7 + GFR1195

Conjugate

Unconjugated

Formulation

PBS with No Preservative

Gene Symbols

EGFR

Immunogen

Human EGFR purified from A431 cells (31G7); Recombinant human EGFR protein (GFR1195)

Quantity

0.1 mg

Research Discipline

Cancer, Cell Biology, Cell Cycle and Replication, Growth and Development, Hypoxia, Signal Transduction, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez)

1956

Target Species

Human

Form

Purified

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Description

  • EGFR Monoclonal specifically detects EGFR in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Flow (Cell Surface), Immunofluorescence, CyTOF-ready.

Compare Similar Items

Show Difference

Img

Fischer Scientific

NBP247743A

--


Antigen:
EGFR

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 2 - 4 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Gene Alias:
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone:
31G7 + GFR1195

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
EGFR

Immunogen:
Human EGFR purified from A431 cells (31G7); Recombinant human EGFR protein (GFR1195)

Quantity:
0.1 mg

Research Discipline:
Cancer, Cell Biology, Cell Cycle and Replication, Growth and Development, Hypoxia, Signal Transduction, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez):
1956

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP247743B

--


Antigen:
EGFR

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 2 - 4 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Gene Alias:
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone:
31G7 + GFR1195

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
EGFR

Immunogen:
Human EGFR purified from A431 cells (31G7); Recombinant human EGFR protein (GFR1195)

Quantity:
0.2 mg

Research Discipline:
Cancer, Cell Biology, Cell Cycle and Replication, Growth and Development, Hypoxia, Signal Transduction, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez):
1956

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP247744A

--


Antigen:
Isocitrate Dehydrogenase 1/IDH1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
Cytosolic NADP-isocitrate dehydrogenase, EC 1.1.1.42, IDCD, IDH, IDP, IDPC, isocitrate dehydrogenase [NADP] cytoplasmic, isocitrate dehydrogenase 1 (NADP+), soluble, NADP(+)-specific ICDH, NADP-dependent isocitrate dehydrogenase, cytosolic, NADP-dependent isocitrate dehydrogenase, peroxisomal, Oxalosuccinate decarboxylase, PICD

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It recognizes a 45kDa protein, which is identified as isocitrate dehydrogenase (IDH1). It belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Recently, an inactivating mutation of IDH1 has been implicated in glioblastoma. IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone:
IDH1/1152

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
IDH1

Immunogen:
Recombinant fragment (119 Amino acid residues around aa 280-420) of human IDH1 protein

Quantity:
0.1 mg

Research Discipline:
Stem Cell Markers

Gene ID (Entrez):
3417

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

NBP247744B

--


Antigen:
Isocitrate Dehydrogenase 1/IDH1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
Cytosolic NADP-isocitrate dehydrogenase, EC 1.1.1.42, IDCD, IDH, IDP, IDPC, isocitrate dehydrogenase [NADP] cytoplasmic, isocitrate dehydrogenase 1 (NADP+), soluble, NADP(+)-specific ICDH, NADP-dependent isocitrate dehydrogenase, cytosolic, NADP-dependent isocitrate dehydrogenase, peroxisomal, Oxalosuccinate decarboxylase, PICD

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It recognizes a 45kDa protein, which is identified as isocitrate dehydrogenase (IDH1). It belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Recently, an inactivating mutation of IDH1 has been implicated in glioblastoma. IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone:
IDH1/1152

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
IDH1

Immunogen:
Recombinant fragment (119 Amino acid residues around aa 280-420) of human IDH1 protein

Quantity:
0.2 mg

Research Discipline:
Stem Cell Markers

Gene ID (Entrez):
3417

Target Species:
Human

Form:
Purified