NBP247745B

Cadherin-16 Antibody (CDH16/1071) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Cadherin-16

Classification

Monoclonal

Concentration

1.0 mg/mL

Dilution

Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Gene Alias

cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin

Host Species

Mouse

Molecular Weight of Antigen

130 kDa

Quantity

0.2 mg

Primary or Secondary

Primary

Test Specificity

This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone

CDH16/1071

Conjugate

Unconjugated

Formulation

PBS with No Preservative

Gene Symbols

CDH16

Immunogen

Recombinant human CDH16 protein

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

1014

Target Species

Human, Mouse, Rat, Canine, Rabbit

Form

Purified

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Description

  • Cadherin-16 Monoclonal specifically detects Cadherin-16 in Human, Mouse, Rat, Canine, Rabbit samples
  • It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.

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Fischer Scientific

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Antigen:
Cadherin-16

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Gene Alias:
cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin

Host Species:
Mouse

Molecular Weight of Antigen:
130 kDa

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone:
CDH16/1071

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
CDH16

Immunogen:
Recombinant human CDH16 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
1014

Target Species:
Human, Mouse, Rat, Canine, Rabbit

Form:
Purified

Img

Fischer Scientific

NBP247746A

--


Antigen:
Cadherin-16

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin

Host Species:
Mouse

Molecular Weight of Antigen:
130 kDa

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), CyTOF

Clone:
SPM594

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
CDH16

Immunogen:
Recombinant human CDH16 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
1014

Target Species:
Human, Mouse, Rat, Canine, Rabbit

Form:
Purified

Img

Fischer Scientific

NBP247746B

--


Antigen:
Cadherin-16

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin

Host Species:
Mouse

Molecular Weight of Antigen:
130 kDa

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), CyTOF

Clone:
SPM594

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
CDH16

Immunogen:
Recombinant human CDH16 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
1014

Target Species:
Human, Mouse, Rat, Canine, Rabbit

Form:
Purified

Img

Fischer Scientific

NBP247748A

--


Antigen:
TOX3

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias:
CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein

Host Species:
Mouse

Molecular Weight of Antigen:
63 kDa

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone:
TOX3/1123

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
TOX3

Immunogen:
Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
27324

Target Species:
Human

Form:
Purified