Manufacturer: Fischer Scientific
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Androgen R/NR3C4
Monoclonal
1.0 mg/mL
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
Mouse
110 kDa
0.2 mg
Breast Cancer, Cancer, Cellular Markers
367
Human, Mouse (Negative)
Purified
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
SPM335
Unconjugated
PBS with No Preservative
AR
A synthetic peptide, aa 299-315, (STEDTAEYSPFKGGYTK) of human AR.
Protein A or G purified
RUO
Primary
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG1 κ