NBP247982B

Cytokeratin 8/18 Antibody (C-43 + DC10) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Cytokeratin 8/18

Classification

Monoclonal

Concentration

1.0 mg/mL

Dilution

Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Gene Alias

CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG

Applications

Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone

C-43 + DC10

Conjugate

Unconjugated

Formulation

PBS with No Preservative

Gene Symbols

KRT8

Immunogen

Keratin preparation from a human carcinoma (C-43); PMC-42 human breast carcinoma cells (DC10)

Quantity

0.2 mg

Research Discipline

Cancer, Cytoskeleton Markers

Gene ID (Entrez)

3856

Target Species

Human

Form

Purified

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Description

  • Cytokeratin 8/18 Monoclonal specifically detects Cytokeratin 8/18 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Fischer Scientific

NBP247982B

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Antigen:
Cytokeratin 8/18

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready

Gene Alias:
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF

Clone:
C-43 + DC10

Conjugate:
Unconjugated

Formulation:
PBS with No Preservative

Gene Symbols:
KRT8

Immunogen:
Keratin preparation from a human carcinoma (C-43); PMC-42 human breast carcinoma cells (DC10)

Quantity:
0.2 mg

Research Discipline:
Cancer, Cytoskeleton Markers

Gene ID (Entrez):
3856

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP247983C

--


Antigen:
Cytokeratin 8/18

Classification:
Monoclonal

Concentration:
__

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immuno-histochemical staining with this monoclonal antibody is indistinguishable from that obtained with monoclonal antibody 5D3.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
KRT8/803 + KRT18/835

Conjugate:
DyLight 650

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
KRT8

Immunogen:
Recombinant full-length human KRT8 protein (KRT8/803); Recombinant full-length human KRT18 protein (KRT18/835)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cytoskeleton Markers, Phospho Specific

Gene ID (Entrez):
3856

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP247983F

--


Antigen:
Cytokeratin 8/18

Classification:
Monoclonal

Concentration:
__

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immuno-histochemical staining with this monoclonal antibody is indistinguishable from that obtained with monoclonal antibody 5D3.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
KRT8/803 + KRT18/835

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
KRT8

Immunogen:
Recombinant full-length human KRT8 protein (KRT8/803); Recombinant full-length human KRT18 protein (KRT18/835)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cytoskeleton Markers, Phospho Specific

Gene ID (Entrez):
3856

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP247983FR

--


Antigen:
Cytokeratin 8/18

Classification:
Monoclonal

Concentration:
__

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immuno-histochemical staining with this monoclonal antibody is indistinguishable from that obtained with monoclonal antibody 5D3.

Content And Storage:
Store at 4C in the dark.

Isotype:
IgG1 κ

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
KRT8/803 + KRT18/835

Conjugate:
DyLight 680

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
KRT8

Immunogen:
Recombinant full-length human KRT8 protein (KRT8/803); Recombinant full-length human KRT18 protein (KRT18/835)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cytoskeleton Markers, Phospho Specific

Gene ID (Entrez):
3856

Target Species:
Human

Form:
Purified