NBP248039

GnRHR Antibody (GNRHR/768) - IHC-Prediluted, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP248039-Each-of-1 In Stock ₹ 44,833.44

NBP248039 - Each of 1

₹ 44,833.44

In Stock

Quantity

1

Base Price: ₹ 44,833.44

GST (18%): ₹ 8,070.019

Total Price: ₹ 52,903.459

Antigen

GnRHR

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols

GNRHR

Immunogen

Recombinant full-length human GNRHR protein

Quantity

7 mL

Research Discipline

GPCR

Gene ID (Entrez)

2798

Target Species

Human

Form

Purified

Applications

Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

GNRHR/768

Dilution

Immunohistochemistry-Paraffin

Gene Alias

GnRH receptor, GnRH-R, GNRHR1, gonadotropin-releasing hormone (type 1) receptor 1, gonadotropin-releasing hormone receptor, GRHR, leutinizing-releasing hormone receptor, LHRHRleutinizing hormone releasing horomone receptor, LRHR, luliberin receptor, type I GnRH receptor

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

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Description

  • GnRHR Monoclonal specifically detects GnRHR in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

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Novus Biologicals

NBP248039

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Antigen:
GnRHR

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
GNRHR

Immunogen:
Recombinant full-length human GNRHR protein

Quantity:
7 mL

Research Discipline:
GPCR

Gene ID (Entrez):
2798

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
GNRHR/768

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
GnRH receptor, GnRH-R, GNRHR1, gonadotropin-releasing hormone (type 1) receptor 1, gonadotropin-releasing hormone receptor, GRHR, leutinizing-releasing hormone receptor, LHRHRleutinizing hormone releasing horomone receptor, LRHR, luliberin receptor, type I GnRH receptor

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR). Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH). GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

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NBP248040

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Antigen:
Golgi Complex

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
__

Immunogen:
SU-DHL-1 large cell lymphoma cells

Quantity:
7 mL

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human, Mouse (Negative), Rat (Negative)

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
AE-6

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes an antigen associated with the Golgi complex in human cells only. It can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This monoclonal antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

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NBP248041

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Antigen:
Cytokeratin 10/13

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
KRT10

Immunogen:
Cytoskeletal preparation extracted from human ectocervical epithelium.

Quantity:
7 mL

Research Discipline:
Cytoskeleton Markers

Gene ID (Entrez):
3858

Target Species:
Human, Feline

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
SPM262

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
BCIE, BIE, CK10, CK-10, cytokeratin 10, Cytokeratin-10, EHK, K10keratosis palmaris et plantaris, keratin 10, keratin, type I cytoskeletal 10, keratin-10, KPP

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes cytokeratin 10 (56.5kDa) and cytokeratin 13 (53kDa) in Western blotting. It recognizes only cytokeratin 13 in formalin-fixed, paraffin-embedded tissue sections. It does not react with cytokeratin 10 positive, cytokeratin 13 negative epithelia such as epidermis. However, on frozen sections this monoclonal antibody serves as differentiation-related marker of all stratified epithelia; it stains all suprabasal cells in both cornifying and non-cornifying stratified epithelia and more differentiated cells of squamous carcinomas.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

Img

Novus Biologicals

NBP248043

--


Antigen:
CEACAM5/CD66e

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
CEACAM5

Immunogen:
Purified human CEACAM5/CD66e protein (Uniprot: P06731)

Quantity:
7 mL

Research Discipline:
Cancer, Cellular Markers, Immunology

Gene ID (Entrez):
1048

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
C66/1260

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This monoclonal antibody reacts with nonspecific cross-reacting antigen (NCA). It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbladder, urachus, salivary gland, ovary, and endocervix.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ