NBP248064
Chromogranin A Antibody (CHGA/765) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248064-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248064 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
Chromogranin A
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
CHGA
Immunogen
Recombinant human Chromogranin A protein (Uniprot: P10645)
Quantity
7 mL
Research Discipline
Apoptosis, Cancer, Neuronal Cell Markers, Tumor Biomarkers
Gene ID (Entrez)
1113
Target Species
Human, Rat (Negative)
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
CHGA/765
Dilution
Immunohistochemistry-Paraffin
Gene Alias
betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Content And Storage
Store at 4C.
Isotype
IgG2a κ
Related Products
Description
- Chromogranin A Monoclonal specifically detects Chromogranin A in Human, Rat (Negative) samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: Chromogranin A
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CHGA
Immunogen: Recombinant human Chromogranin A protein (Uniprot: P10645)
Quantity: 7 mL
Research Discipline: Apoptosis, Cancer, Neuronal Cell Markers, Tumor Biomarkers
Gene ID (Entrez): 1113
Target Species: Human, Rat (Negative)
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CHGA/765
Dilution: Immunohistochemistry-Paraffin
Gene Alias: betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Antigen:
Chromogranin A
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CHGA
Immunogen:
Recombinant human Chromogranin A protein (Uniprot: P10645)
Quantity:
7 mL
Research Discipline:
Apoptosis, Cancer, Neuronal Cell Markers, Tumor Biomarkers
Gene ID (Entrez):
1113
Target Species:
Human, Rat (Negative)
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CHGA/765
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Antigen: Cytokeratin 18
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: KRT18
Immunogen: Recombinant full-length human Cytokeratin 18 protein (Uniprot: P05783)
Quantity: 7 mL
Research Discipline: Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers
Gene ID (Entrez): 3875
Target Species: Human, Canine, Feline, Rat (Negative)
Form: Purified
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Clone: KRT18/836
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array
Gene Alias: Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Cytokeratin 18
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
KRT18
Immunogen:
Recombinant full-length human Cytokeratin 18 protein (Uniprot: P05783)
Quantity:
7 mL
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers
Gene ID (Entrez):
3875
Target Species:
Human, Canine, Feline, Rat (Negative)
Form:
Purified
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array
Clone:
KRT18/836
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array
Gene Alias:
Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: hCG holo C2
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CGB3
Immunogen: Purified hCG protein
Quantity: 7 mL
Research Discipline: Cancer
Gene ID (Entrez): 1082
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: HCGab/52
Dilution: Immunohistochemistry-Paraffin
Gene Alias: choriogonadotropin subunit beta, CGB3, CGB5, CGB7, CGB8, chorionic gonadotropin, beta polypeptide, hCGB
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
hCG holo C2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CGB3
Immunogen:
Purified hCG protein
Quantity:
7 mL
Research Discipline:
Cancer
Gene ID (Entrez):
1082
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
HCGab/52
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
choriogonadotropin subunit beta, CGB3, CGB5, CGB7, CGB8, chorionic gonadotropin, beta polypeptide, hCGB
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Hepatocyte Specific Antigen
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: __
Immunogen: Extract of a formalin-fixed, rejected-allograft of a human liver
Quantity: 7 mL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse, Canine
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: HepPar1
Dilution: Immunohistochemistry-Paraffin
Gene Alias: Hepatocyte, HSA
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Hepatocyte Paraffin 1 or HepPar1 localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Hepatocyte Specific Antigen
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
__
Immunogen:
Extract of a formalin-fixed, rejected-allograft of a human liver
Quantity:
7 mL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse, Canine
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
HepPar1
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
Hepatocyte, HSA
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Hepatocyte Paraffin 1 or HepPar1 localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ