NBP248075

Cytokeratin 18 Antibody (C-04 (same as Ks18.04)) - IHC-Prediluted, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP248075-Each-of-1 In Stock ₹ 44,833.44

NBP248075 - Each of 1

₹ 44,833.44

In Stock

Quantity

1

Base Price: ₹ 44,833.44

GST (18%): ₹ 8,070.019

Total Price: ₹ 52,903.459

Antigen

Cytokeratin 18

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols

KRT18

Immunogen

Cytoskeletal preparation extracted from the human vulvar squamous carcinoma cell line A431.

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

Applications

Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

C-04 (same as Ks18.04)

Dilution

Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias

Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18

Host Species

Mouse

Molecular Weight of Antigen

45 kDa

Quantity

7 mL

Research Discipline

Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers

Gene ID (Entrez)

3875

Target Species

Human, Mouse, Rat, Porcine, Canine, Equine, Feline, Goat, Hamster, Ferret, Monkey, Primate, Sheep, Chicken (Negative), Xenopus (Negative)

Form

Purified

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Description

  • Cytokeratin 18 Monoclonal specifically detects Cytokeratin 18 in Human, Mouse, Rat, Porcine, Bovine, Canine, Equine, Feline, Goat, Hamster, Ferret, Monkey, Sheep, Chicken (Negative), Xenopus (Negative) samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

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Novus Biologicals

NBP248075

--


Antigen:
Cytokeratin 18

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
KRT18

Immunogen:
Cytoskeletal preparation extracted from the human vulvar squamous carcinoma cell line A431.

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
C-04 (same as Ks18.04)

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18

Host Species:
Mouse

Molecular Weight of Antigen:
45 kDa

Quantity:
7 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers

Gene ID (Entrez):
3875

Target Species:
Human, Mouse, Rat, Porcine, Canine, Equine, Feline, Goat, Hamster, Ferret, Monkey, Primate, Sheep, Chicken (Negative), Xenopus (Negative)

Form:
Purified

Img

Novus Biologicals

NBP248076

--


Antigen:
Cytokeratin 18

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
KRT18

Immunogen:
Recombinant full-length human Cytokeratin 18 protein (Uniprot: P05783)

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
Cocktail

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18

Host Species:
Mouse

Molecular Weight of Antigen:
45 kDa

Quantity:
7 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers

Gene ID (Entrez):
3875

Target Species:
Human

Form:
Purified

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NBP248078

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Antigen:
H1F0

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
H1-0

Immunogen:
Nuclei of human leukemia biopsy cells

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
1415-1

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
H1 histone family, member 0, H1.0, H1(0), H1-0, H10, H1FVMGC5241, Histone H1', Histone H1(0), histone H1.0

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
7 mL

Research Discipline:
Cellular Markers, Chromatin Research, Epigenetics, Histones and Modified Histones, Nuclear Envelope Markers

Gene ID (Entrez):
3005

Target Species:
Human, Mouse, Rat

Form:
Purified

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NBP248079

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Antigen:
Lewis A Blood Group Antigen

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
ABO

Immunogen:
Mucins isolated from ovarian cyst fluid

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
SPM279

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
A transferase, A3GALNT, A3GALT1, ABO, B transferase, EC=2.4.1.37, EC=2.4.1.40, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, GTB, Histo-blood group A transferase, Histo-blood group ABO system transferase, Histo-blood group B transferase, NAGAT

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
7 mL

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human, Mouse

Form:
Purified