NBP248138
Macrophage and Histiocytoma Marker Antibody (D11) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248138-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248138 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
Macrophage and Histiocytoma Marker
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10 mM PBS with 0.05% Sodium Azide
Immunogen
Membrane preparation from human hepatocytes
Quantity
7 mL
Primary or Secondary
Primary
Target Species
Human, Mouse (Negative), Porcine (Negative), Rat (Negative)
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
D11
Dilution
Immunohistochemistry-Paraffin
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Test Specificity
In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this monoclonal antibody and a standard CD68 monoclonal antibody showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This monoclonal antibody shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This monoclonal antibody does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- Macrophage and Histiocytoma Marker Monoclonal specifically detects Macrophage and Histiocytoma Marker in Human, Mouse (Negative), Porcine (Negative), Rat (Negative) samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: Macrophage and Histiocytoma Marker
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10 mM PBS with 0.05% Sodium Azide
Immunogen: Membrane preparation from human hepatocytes
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human, Mouse (Negative), Porcine (Negative), Rat (Negative)
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: D11
Dilution: Immunohistochemistry-Paraffin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this monoclonal antibody and a standard CD68 monoclonal antibody showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This monoclonal antibody shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This monoclonal antibody does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Macrophage and Histiocytoma Marker
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10 mM PBS with 0.05% Sodium Azide
Immunogen:
Membrane preparation from human hepatocytes
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse (Negative), Porcine (Negative), Rat (Negative)
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
D11
Dilution:
Immunohistochemistry-Paraffin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this monoclonal antibody and a standard CD68 monoclonal antibody showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This monoclonal antibody shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This monoclonal antibody does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Cytokeratin 7
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen: Recombinant full-length human Cytokeratin 7 protein (Uniprot: P08729)
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: KRT7/760
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This monoclonal antibody is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This monoclonal antibody is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Cytokeratin 7
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Recombinant full-length human Cytokeratin 7 protein (Uniprot: P08729)
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
KRT7/760
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This monoclonal antibody is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This monoclonal antibody is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: DNA
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen: Nuclei of Burkitt's cells
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: DSD/958
Dilution: Immunohistochemistry-Paraffin
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Test Specificity: This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This monoclonal antibody recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This monoclonal antibody produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.
Content And Storage: Store at 4C.
Isotype: IgG3 κ
Antigen:
DNA
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Nuclei of Burkitt's cells
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
DSD/958
Dilution:
Immunohistochemistry-Paraffin
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Test Specificity:
This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This monoclonal antibody recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This monoclonal antibody produces a homogeneous staining pattern in the nucleus of normal and malignant cells. Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.
Content And Storage:
Store at 4C.
Isotype:
IgG3 κ
Antigen: Cytokeratin 7
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen: Recombinant full-length human Cytokeratin 7 protein (Uniprot: P08729)
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: KRT7/760 + KRT7/903
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This monoclonal antibody is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This monoclonal antibody is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Cytokeratin 7
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Immunogen:
Recombinant full-length human Cytokeratin 7 protein (Uniprot: P08729)
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
KRT7/760 + KRT7/903
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This monoclonal antibody is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This monoclonal antibody is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ