NBP248180
Cytokeratin 8/18 Antibody (B22.1/B23.1) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248180-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
Cytokeratin 8/18
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
KRT8
Immunogen
Cytoskeletal preparation from HeLa epitheliod carcinoma cells (B22.1) and PMC-42 breast carcinoma cells of human origin (B23.1)
Quantity
7 mL
Research Discipline
Cancer, Cytoskeleton Markers
Gene ID (Entrez)
3856
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
B22.1/B23.1
Dilution
Immunohistochemistry-Paraffin
Gene Alias
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained. Immunohistochemical staining with this monoclonal antibody is indistinguishable from that obtained with monoclonal antibody 5D3.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- Cytokeratin 8/18 Monoclonal specifically detects Cytokeratin 8/18 in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Cytokeratin 8/18
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: KRT8
Immunogen: Cytoskeletal preparation from HeLa epitheliod carcinoma cells (B22.1) and PMC-42 breast carcinoma cells of human origin (B23.1)
Quantity: 7 mL
Research Discipline: Cancer, Cytoskeleton Markers
Gene ID (Entrez): 3856
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: B22.1/B23.1
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained. Immunohistochemical staining with this monoclonal antibody is indistinguishable from that obtained with monoclonal antibody 5D3.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Cytokeratin 8/18
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
KRT8
Immunogen:
Cytoskeletal preparation from HeLa epitheliod carcinoma cells (B22.1) and PMC-42 breast carcinoma cells of human origin (B23.1)
Quantity:
7 mL
Research Discipline:
Cancer, Cytoskeleton Markers
Gene ID (Entrez):
3856
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
B22.1/B23.1
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained. Immunohistochemical staining with this monoclonal antibody is indistinguishable from that obtained with monoclonal antibody 5D3.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Caldesmon/CALD1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CALD1
Immunogen: Crude human uterus extract
Quantity: 7 mL
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 800
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: SPM168
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (12080kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This monoclonal antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Caldesmon/CALD1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CALD1
Immunogen:
Crude human uterus extract
Quantity:
7 mL
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
800
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM168
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (12080kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This monoclonal antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Caldesmon/CALD1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CALD1
Immunogen: Recombinant full-length human Caldesmon/CALD1 protein (Uniprot: Q05682)
Quantity: 7 mL
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 800
Target Species: Human, Rat (Negative)
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CALD1/820
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (12080kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This monoclonal antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Caldesmon/CALD1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CALD1
Immunogen:
Recombinant full-length human Caldesmon/CALD1 protein (Uniprot: Q05682)
Quantity:
7 mL
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
800
Target Species:
Human, Rat (Negative)
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CALD1/820
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (12080kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This monoclonal antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Caldesmon/CALD1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CALD1
Immunogen: Recombinant full-length human Caldesmon/CALD1 protein (Caldesmon/CALD1/820); Crude human uterus extract (h-CALD) (Uniprot: Q05682)
Quantity: 7 mL
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 800
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CALD1/820 + h-CALD
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This monoclonal antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Caldesmon/CALD1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CALD1
Immunogen:
Recombinant full-length human Caldesmon/CALD1 protein (Caldesmon/CALD1/820); Crude human uterus extract (h-CALD) (Uniprot: Q05682)
Quantity:
7 mL
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
800
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CALD1/820 + h-CALD
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This monoclonal antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ