NBP248296
NGFR/TNFRSF16/p75NTR Antibody (SPM299) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248296-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248296 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
NGFR/TNFRSF16/p75NTR
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
NGFR
Immunogen
NGFR from A875 melanoma cells
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin)
Clone
SPM299
Dilution
Immunohistochemistry-Paraffin
Gene Alias
CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species
Mouse
Molecular Weight of Antigen
75 kDa
Quantity
7 mL
Research Discipline
Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez)
4804
Target Species
Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative)
Form
Purified
Related Products
Description
- NGFR/TNFRSF16/p75NTR Monoclonal specifically detects NGFR/TNFRSF16/p75NTR in Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative) samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: NGFR/TNFRSF16/p75NTR
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: NGFR
Immunogen: NGFR from A875 melanoma cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: SPM299
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 7 mL
Research Discipline: Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez): 4804
Target Species: Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
NGFR/TNFRSF16/p75NTR
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
NGFR
Immunogen:
NGFR from A875 melanoma cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM299
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
7 mL
Research Discipline:
Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez):
4804
Target Species:
Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative)
Form:
Purified
Antigen: NGFR/TNFRSF16/p75NTR
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: NGFR
Immunogen: Recombinant human NGFR/TNFRSF16/p75NTR protein (Uniprot: P08138)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: NTR/912
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 7 mL
Research Discipline: Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez): 4804
Target Species: Human, Primate, Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
NGFR/TNFRSF16/p75NTR
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
NGFR
Immunogen:
Recombinant human NGFR/TNFRSF16/p75NTR protein (Uniprot: P08138)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
NTR/912
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
7 mL
Research Discipline:
Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez):
4804
Target Species:
Human, Primate, Mouse (Negative), Rat (Negative)
Form:
Purified
Antigen: Cytokeratin, pan
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: KRT1
Immunogen: This Cytokeratin, pan Antibody (PAN-CK (Cocktail)) was developed against human epidermal keratin.
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 55kDa (CK7); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 46kDa (CK17); 45kDa (CK18) and 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad-spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.
Content And Storage: Store at 4C.
Isotype: IgG κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: PAN-CK (Cocktail)
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: __
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Research Discipline: Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction
Gene ID (Entrez): 3848
Target Species: Human, Mouse, Rat, Canine, Chicken, Monkey, Primate, Rabbit
Form: Purified
Antigen:
Cytokeratin, pan
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10 mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
KRT1
Immunogen:
This Cytokeratin, pan Antibody (PAN-CK (Cocktail)) was developed against human epidermal keratin.
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 55kDa (CK7); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 46kDa (CK17); 45kDa (CK18) and 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad-spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.
Content And Storage:
Store at 4C.
Isotype:
IgG κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
PAN-CK (Cocktail)
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
__
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Research Discipline:
Apoptosis, Cancer, Cell Biology, Cellular Markers, Signal Transduction
Gene ID (Entrez):
3848
Target Species:
Human, Mouse, Rat, Canine, Chicken, Monkey, Primate, Rabbit
Form:
Purified
Antigen: Bcl-2
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: BCL2
Immunogen: Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: BCL2/782 + BCL2/796
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species: Mouse
Molecular Weight of Antigen: 25.5 kDa
Quantity: 7 mL
Research Discipline: Apoptosis, Autophagy, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Tumor Suppressors
Gene ID (Entrez): 596
Target Species: Human
Form: Purified
Antigen:
Bcl-2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
BCL2
Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
BCL2/782 + BCL2/796
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species:
Mouse
Molecular Weight of Antigen:
25.5 kDa
Quantity:
7 mL
Research Discipline:
Apoptosis, Autophagy, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Tumor Suppressors
Gene ID (Entrez):
596
Target Species:
Human
Form:
Purified