NBP248332

CD34 Antibody (HPCA1/763) - IHC-Prediluted, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP248332-Each-of-1 In Stock ₹ 45,860.16

NBP248332 - Each of 1

₹ 45,860.16

In Stock

Quantity

1

Base Price: ₹ 45,860.16

GST (18%): ₹ 8,254.829

Total Price: ₹ 54,114.989

Antigen

CD34

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols

CD34

Immunogen

Recombinant full-length human CD34 protein (Uniprot: P28906)

Quantity

7 mL

Research Discipline

Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez)

947

Target Species

Human

Form

Purified

Applications

Immunohistochemistry (Paraffin)

Clone

HPCA1/763

Dilution

Immunohistochemistry-Paraffin

Gene Alias

CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.

Content And Storage

Store at 4C.

Isotype

IgG1 λ

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Description

  • CD34 Monoclonal specifically detects CD34 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

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Novus Biologicals

NBP248332

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Antigen:
CD34

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
CD34

Immunogen:
Recombinant full-length human CD34 protein (Uniprot: P28906)

Quantity:
7 mL

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez):
947

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
HPCA1/763

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.

Content And Storage:
Store at 4C.

Isotype:
IgG1 λ

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NBP248333

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Antigen:
Kallikrein 3/PSA

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
KLK3

Immunogen:
Recombinant full-length human Kallikrein 3/PSA protein (Uniprot: P07288)

Quantity:
7 mL

Research Discipline:
Cancer, Cellular Markers, Prostate Cancer, Tumor Biomarkers

Gene ID (Entrez):
354

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
KLK3/1248

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
APS seminin, EC 3.4.21, EC 3.4.21.77, Gamma-seminoprotein, hK3, kallikrein 3, (prostate specific antigen), Kallikrein-3, kallikrein-related peptidase 3, KLK2A1, P-30 antigen, prostate specific antigen, prostate-specific antigen, PSA, PSA semenogelase, Semenogelase, Seminin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This monoclonal antibody is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This monoclonal antibody makes an excellent pair with monoclonal antibody A67-B/E3 for PSA tests.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP248334

--


Antigen:
Kallikrein 3/PSA

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
KLK3

Immunogen:
Kallikrein 3/PSA from human sperm plasma (Uniprot: P07288)

Quantity:
7 mL

Research Discipline:
Cancer, Cellular Markers, Prostate Cancer, Tumor Biomarkers

Gene ID (Entrez):
354

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
A67-B/E3 + 1A7

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
APS seminin, EC 3.4.21, EC 3.4.21.77, Gamma-seminoprotein, hK3, kallikrein 3, (prostate specific antigen), Kallikrein-3, kallikrein-related peptidase 3, KLK2A1, P-30 antigen, prostate specific antigen, prostate-specific antigen, PSA, PSA semenogelase, Semenogelase, Seminin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This monoclonal antibody is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

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NBP248335

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Antigen:
CD20

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
MS4A1

Immunogen:
Recombinant full-length human CD20 protein (Uniprot: P11836 )

Quantity:
7 mL

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cancer, Cancer Stem Cells, Cell Biology, Cytokine Research, Immunology, Signal Transduction, Stem Cell Markers, Tumor Biomarkers

Gene ID (Entrez):
931

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
IGEL/773

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
B1, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35MGC3969, CD20 antigen, CD20 receptor, CD20S7, CVID5, LEU-16, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, MS4A2

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 30-33kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This monoclonal antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ