NBP248359

MUC1 Antibody (HMPV) - IHC-Prediluted, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP248359-Each-of-1 In Stock ₹ 44,833.44

NBP248359 - Each of 1

₹ 44,833.44

In Stock

Quantity

1

Base Price: ₹ 44,833.44

GST (18%): ₹ 8,070.019

Total Price: ₹ 52,903.459

Antigen

MUC-1

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols

MUC1

Immunogen

Human breast cancer cell line ZR-75 cells

Quantity

7 mL

Research Discipline

Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction

Gene ID (Entrez)

4582

Target Species

Human

Form

Purified

Applications

Immunohistochemistry (Paraffin)

Clone

HMPV

Dilution

Immunohistochemistry-Paraffin

Gene Alias

Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this monoclonal antibody is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (200kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the monoclonal antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This monoclonal antibody reacts with both normal and malignant epithelia of various tissues including breast and colon.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

Related Products

Img

Novus Biologicals

NBP248378

--

Img

Novus Biologicals

NBP248377

--

Img

Novus Biologicals

NBP248376

--

Img

Novus Biologicals

NBP248417

--

Img

Novus Biologicals

NBP248428

--

Img

Novus Biologicals

NBP248414

--

Img

Novus Biologicals

NBP248427

--

Img

Novus Biologicals

NBP248429

--

Description

  • MUC1 Monoclonal specifically detects MUC1 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP248359

--


Antigen:
MUC-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
MUC1

Immunogen:
Human breast cancer cell line ZR-75 cells

Quantity:
7 mL

Research Discipline:
Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction

Gene ID (Entrez):
4582

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
HMPV

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this monoclonal antibody is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (200kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the monoclonal antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This monoclonal antibody reacts with both normal and malignant epithelia of various tissues including breast and colon.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP248362

--


Antigen:
CD34

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
CD34

Immunogen:
Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)

Quantity:
7 mL

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez):
947

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
QBEnd/10 + HPCA1/763

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.

Content And Storage:
Store at 4C.

Isotype:
IgG1 λ

Img

Novus Biologicals

NBP248363

--


Antigen:
CD34

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
CD34

Immunogen:
Recombinant full-length human CD34 protein (Uniprot: P28906)

Quantity:
7 mL

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez):
947

Target Species:
Human, Rat

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
HPCA1/1171

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but shows low specificity.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP248364

--


Antigen:
CD34

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
CD34

Immunogen:
Recombinant full-length human CD34 protein (Uniprot: P28906)

Quantity:
7 mL

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Gene ID (Entrez):
947

Target Species:
Human, Rat

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
SPM610

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposi s sarcoma, but shows low specificity.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ