NBP248370

SSEA-1 Antibody (FUT4/815) - IHC-Prediluted, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP248370-Each-of-1 In Stock ₹ 43,336.14

NBP248370 - Each of 1

₹ 43,336.14

In Stock

Quantity

1

Base Price: ₹ 43,336.14

GST (18%): ₹ 7,800.505

Total Price: ₹ 51,136.645

Antigen

SSEA-1

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Host Species

Mouse

Purification Method

Protein L or PEG purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Content And Storage

Store at 4C.

Isotype

IgM κ

Applications

Immunohistochemistry (Paraffin)

Clone

FUT4/815

Dilution

Immunohistochemistry-Paraffin

Gene Alias

alpha-(1,3)-fucosyltransferase, CD15, EC 2.4.1, EC 2.4.1.-, EC 2.4.1.65, ELAM-1 ligand fucosyltransferase, ELFT, FCT3AELAM ligand fucosyltransferase, Fucosyltransferase 4, fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), Fucosyltransferase IV, fucT-IV, FUC-TIV, FUTIV, Galactoside 3-L-fucosyltransferase, Lewis X, LeX, SSEA-1, stage-specific embryonic antigen 1

Immunogen

Purified human SSEA-1 (Uniprot: P22083)

Quantity

7 mL

Research Discipline

Cellular Markers, Embryonic Stem Cell Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Immunology, Pancreatic Stem Cell Markers, Stem Cell Markers, Stem Cells

Gene ID (Entrez)

2526

Target Species

Human, Mouse, Rat

Form

Purified

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Description

  • SSEA-1 Monoclonal specifically detects SSEA-1 in Human, Mouse, Rat samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Img

Novus Biologicals

NBP248370

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Antigen:
SSEA-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Host Species:
Mouse

Purification Method:
Protein L or PEG purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Content And Storage:
Store at 4C.

Isotype:
IgM κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
FUT4/815

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
alpha-(1,3)-fucosyltransferase, CD15, EC 2.4.1, EC 2.4.1.-, EC 2.4.1.65, ELAM-1 ligand fucosyltransferase, ELFT, FCT3AELAM ligand fucosyltransferase, Fucosyltransferase 4, fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific), Fucosyltransferase IV, fucT-IV, FUC-TIV, FUTIV, Galactoside 3-L-fucosyltransferase, Lewis X, LeX, SSEA-1, stage-specific embryonic antigen 1

Immunogen:
Purified human SSEA-1 (Uniprot: P22083)

Quantity:
7 mL

Research Discipline:
Cellular Markers, Embryonic Stem Cell Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Immunology, Pancreatic Stem Cell Markers, Stem Cell Markers, Stem Cells

Gene ID (Entrez):
2526

Target Species:
Human, Mouse, Rat

Form:
Purified

Img

Novus Biologicals

NBP248371

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Antigen:
p21/CIP1/CDKN1A

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
CIP1/823

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1

Immunogen:
Recombinant full-length human p21/CIP1/CDKN1A protein (Uniprot: P38936)

Quantity:
7 mL

Research Discipline:
Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair

Gene ID (Entrez):
1026

Target Species:
Human, Mouse (Negative), Rat (Negative)

Form:
Purified

Img

Novus Biologicals

NBP248373

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Antigen:
Bromodeoxyuridine/BrdU

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It reacts with Bromodeoxyuridine (BrdU) in single stranded DNA (produced by partial denaturation of double stranded DNA), BrdU coupled to a protein carrier, as well as free BrdU. BrdU is a thymidine analog, incorporated into cell nuclei during DNA synthesis prior to mitosis. Antibody to BrdU is helpful in detecting S-phase cells, providing useful information on the aggressiveness of tumors.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
MoBu-1

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
Bromodeoxyuridine, BUdr

Immunogen:
Bromodeoxyuridine (BrdU) conjugated to hemocyanine (isolated from Helix pomatia)

Quantity:
7 mL

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
All species

Form:
Purified

Img

Novus Biologicals

NBP248375

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Antigen:
MUC-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

Content And Storage:
Store at 4C.

Isotype:
IgG2a λ

Applications:
Immunohistochemistry (Paraffin)

Clone:
MUC1/520

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Immunogen:
Human milk-fat globule membranes (HMFGM) (Uniprot: P15941 )

Quantity:
7 mL

Research Discipline:
Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction

Gene ID (Entrez):
4582

Target Species:
Human

Form:
Purified