NBP248398
Glypican 3 Antibody (GPC3/863) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248398-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248398 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
Glypican 3
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
GPC3
Immunogen
Recombinant full-length human Glypican 3 protein (Uniprot: P51654)
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
2719
Target Species
Human, Rat
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
GPC3/863
Dilution
Immunohistochemistry-Paraffin
Gene Alias
DGSX, glypican 3, glypican proteoglycan 3, glypican-3, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, OCI5, OCI-5, secreted glypican-3, SGB, SGBS, SGBS1SDYS
Host Species
Mouse
Molecular Weight of Antigen
67 kDa
Quantity
7 mL
Primary or Secondary
Primary
Test Specificity
Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- Glypican 3 Monoclonal specifically detects Glypican 3 in Human, Rat samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: Glypican 3
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: GPC3
Immunogen: Recombinant full-length human Glypican 3 protein (Uniprot: P51654)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 2719
Target Species: Human, Rat
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: GPC3/863
Dilution: Immunohistochemistry-Paraffin
Gene Alias: DGSX, glypican 3, glypican proteoglycan 3, glypican-3, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, OCI5, OCI-5, secreted glypican-3, SGB, SGBS, SGBS1SDYS
Host Species: Mouse
Molecular Weight of Antigen: 67 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Glypican 3
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
GPC3
Immunogen:
Recombinant full-length human Glypican 3 protein (Uniprot: P51654)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
2719
Target Species:
Human, Rat
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
GPC3/863
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
DGSX, glypican 3, glypican proteoglycan 3, glypican-3, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, OCI5, OCI-5, secreted glypican-3, SGB, SGBS, SGBS1SDYS
Host Species:
Mouse
Molecular Weight of Antigen:
67 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
Glypican-3 (GPC3) is a glycosylphospatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Anti-GPC3 has been identified as a useful tumor marker for the diagnosis of hepatocellular carcinoma (HCC), hepatoblastoma, melanoma, testicular germ cell tumors, and Wilms tumor and hepatoblastoma, with a low or undetectable expression in normal adjacent tissue. In patients with thyroid cancer, expression of GPC3 is dramatically enhanced in certain types of cancers: 100% in follicular carcinoma and 70% in papillary carcinoma. Expression of GPC3 in follicular carcinoma is significantly higher than that of follicular adenoma. In contrast, GPC3 is not expressed in anaplastic carcinoma.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: p27/Kip1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CDKN1B
Immunogen: Recombinant full-length human p27/Kip1 protein (Uniprot: P46527)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 1027
Target Species: Human, Mouse, Rat, Monkey
Form: Purified
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: KIP1/769
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: CDKN4, cyclin-dependent kinase inhibitor 1B, cyclin-dependent kinase inhibitor 1B (p27, Kip1), Cyclin-dependent kinase inhibitor p27, KIP1P27KIP1, MEN1B, MEN4, p27Kip1
Host Species: Mouse
Molecular Weight of Antigen: 25.5 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This monoclonal antibody is excellent for staining of formalin-fixed tissues.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
p27/Kip1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CDKN1B
Immunogen:
Recombinant full-length human p27/Kip1 protein (Uniprot: P46527)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
1027
Target Species:
Human, Mouse, Rat, Monkey
Form:
Purified
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
KIP1/769
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
CDKN4, cyclin-dependent kinase inhibitor 1B, cyclin-dependent kinase inhibitor 1B (p27, Kip1), Cyclin-dependent kinase inhibitor p27, KIP1P27KIP1, MEN1B, MEN4, p27Kip1
Host Species:
Mouse
Molecular Weight of Antigen:
25.5 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This monoclonal antibody is excellent for staining of formalin-fixed tissues.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: p27/Kip1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CDKN1B
Immunogen: Mouse recombinant p27/Kip1 protein (DCS-72.F6); Recombinant human CDKN1B protein (KIP1/769) (Uniprot: P46527)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 1027
Target Species: Human, Mouse, Rat, Monkey
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: DCS-72.F6 + KIP1/769
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CDKN4, cyclin-dependent kinase inhibitor 1B, cyclin-dependent kinase inhibitor 1B (p27, Kip1), Cyclin-dependent kinase inhibitor p27, KIP1P27KIP1, MEN1B, MEN4, p27Kip1
Host Species: Mouse
Molecular Weight of Antigen: 25.5 kDa
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This monoclonal antibody co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
p27/Kip1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CDKN1B
Immunogen:
Mouse recombinant p27/Kip1 protein (DCS-72.F6); Recombinant human CDKN1B protein (KIP1/769) (Uniprot: P46527)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
1027
Target Species:
Human, Mouse, Rat, Monkey
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
DCS-72.F6 + KIP1/769
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CDKN4, cyclin-dependent kinase inhibitor 1B, cyclin-dependent kinase inhibitor 1B (p27, Kip1), Cyclin-dependent kinase inhibitor p27, KIP1P27KIP1, MEN1B, MEN4, p27Kip1
Host Species:
Mouse
Molecular Weight of Antigen:
25.5 kDa
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This monoclonal antibody co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Retinol Binding Protein RBP
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: RBP1
Immunogen: Recombinant human retinol binding protein-1 (RBP1)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 5947
Target Species: Human, Mouse, Rat, Goat, Monkey, Rabbit
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: RBP/872
Dilution: Immunohistochemistry-Paraffin
Gene Alias: C, Cellular retinol-binding protein, CRABP-I, CRBP1CRBP-I, CRBPCellular retinol-binding protein I, CRBPI, RBPC, retinol binding protein 1, cellular, retinol-binding protein 1, retinol-binding protein 1, cellular
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 7 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Retinol Binding Protein RBP
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
RBP1
Immunogen:
Recombinant human retinol binding protein-1 (RBP1)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
5947
Target Species:
Human, Mouse, Rat, Goat, Monkey, Rabbit
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
RBP/872
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
C, Cellular retinol-binding protein, CRABP-I, CRBP1CRBP-I, CRBPCellular retinol-binding protein I, CRBPI, RBPC, retinol binding protein 1, cellular, retinol-binding protein 1, retinol-binding protein 1, cellular
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
7 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ