NBP248443

Myosin heavy chain 11 Antibody (SMMS-1) - IHC-Prediluted, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP248443-Each-of-1 In Stock ₹ 44,833.44

NBP248443 - Each of 1

₹ 44,833.44

In Stock

Quantity

1

Base Price: ₹ 44,833.44

GST (18%): ₹ 8,070.019

Total Price: ₹ 52,903.459

Antigen

Myosin heavy chain 11

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols

MYH11

Immunogen

Human uterus extract (Uniprot: P35749)

Quantity

7 mL

Research Discipline

Hypoxia, Stem Cell Markers

Gene ID (Entrez)

4629

Target Species

Human, Rat, Porcine, Canine, Chicken, Feline, Guinea Pig, Primate, Rabbit

Form

Purified

Applications

Immunohistochemistry (Paraffin)

Clone

SMMS-1

Dilution

Immunohistochemistry-Paraffin

Gene Alias

AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

Related Products

Img

Novus Biologicals

NBP248446

--

Img

Novus Biologicals

NBP248447

--

Img

Novus Biologicals

NBP248149

--

Img

Novus Biologicals

NBP248150

--

Img

Novus Biologicals

NBP247901G

--

Img

Novus Biologicals

NBP248204

--

Img

Novus Biologicals

NBP248205

--

Img

Novus Biologicals

NBP248206

--

Description

  • Myosin heavy chain 11 Monoclonal specifically detects Myosin heavy chain 11 in Human, Rat, Porcine, Bovine, Canine, Chicken, Feline, Guinea Pig, Rabbit samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP248443

--


Antigen:
Myosin heavy chain 11

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
MYH11

Immunogen:
Human uterus extract (Uniprot: P35749)

Quantity:
7 mL

Research Discipline:
Hypoxia, Stem Cell Markers

Gene ID (Entrez):
4629

Target Species:
Human, Rat, Porcine, Canine, Chicken, Feline, Guinea Pig, Primate, Rabbit

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
SMMS-1

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP248444

--


Antigen:
SOX10

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
SOX10

Immunogen:
Recombinant fragment (aa 115-269) of human SOX10 protein with hexa-histidine tag (Uniprot: P56693)

Quantity:
7 mL

Research Discipline:
__

Gene ID (Entrez):
6663

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
SPM607

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4C, WS4mouse, human homolog of

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of ∼55kDa, identified as SOX10. This monoclonal antibody is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Img

Novus Biologicals

NBP248446

--


Antigen:
Myosin heavy chain 11

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
MYH11

Immunogen:
Human uterus extract (Uniprot: P35749)

Quantity:
7 mL

Research Discipline:
Hypoxia, Stem Cell Markers

Gene ID (Entrez):
4629

Target Species:
Human, Rat, Porcine, Canine, Chicken, Feline, Guinea Pig, Primate, Rabbit

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
SPM201

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP248447

--


Antigen:
Myosin heavy chain 11

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Symbols:
MYH11

Immunogen:
Human uterus extract (Uniprot: P35749)

Quantity:
7 mL

Research Discipline:
Hypoxia, Stem Cell Markers

Gene ID (Entrez):
4629

Target Species:
Human, Rat, Porcine, Canine, Chicken, Feline, Guinea Pig, Primate, Rabbit

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
ID8

Dilution:
Immunohistochemistry-Paraffin

Gene Alias:
AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ