NBP254366G

Filaggrin Antibody (FLG/1561), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP254366G-Each-of-1 In Stock ₹ 55,271.76

NBP254366G - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Filaggrin

Classification

Monoclonal

Conjugate

DyLight 488

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

FLG

Immunogen

Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary) (Uniprot: P20930)

Primary or Secondary

Primary

Test Specificity

Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

Content And Storage

Store at 4°C in the dark.

Applications

Immunohistochemistry, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence

Clone

FLG/1561

Dilution

Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias

ATOD2, epidermal filaggrin, filaggrin, Profilaggrin

Host Species

Mouse

Quantity

0.1 mL

Gene ID (Entrez)

2312

Target Species

Human

Isotype

IgG1 κ

Description

  • Filaggrin Monoclonal specifically detects Filaggrin in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

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Novus Biologicals

NBP254366G

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Antigen:
Filaggrin

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
FLG

Immunogen:
Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary) (Uniprot: P20930)

Primary or Secondary:
Primary

Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence

Clone:
FLG/1561

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
2312

Target Species:
Human

Isotype:
IgG1 κ

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Novus Biologicals

NBP254367G

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Antigen:
Connexin 32/GJB1

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
GJB1

Immunogen:
Rat junctional complexes

Primary or Secondary:
Primary

Test Specificity:
This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called 'connexons' that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane therefore, one connexin usually cannot fully substitute for another.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
M12.13

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Alias:
CMTX, Connexin-32, Cx32, CX32beta 1, 32kD (connexin 32, Charcot-Marie-Toothneuropathy, X-linked), gap junction beta-1 protein, gap junction protein, beta 1, 32kDa, gap junction protein, beta 1, 32kDa (connexin 32), gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Toothneuropathy, X-linked)

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
2705

Target Species:
Human, Mouse, Rat

Isotype:
IgG

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Novus Biologicals

NBP254368G

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Antigen:
CFTR

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
CFTR

Immunogen:
Recombinant fragment (around aa 258-385) of human CFTR protein (exact sequence is proprietary) (Uniprot: P13569)

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
CFTR/1775R

Dilution:
Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
ABC35, ABCC7CF, ATP-binding cassette sub-family C member 7, ATP-binding cassette transporter sub-family C member 7, cAMP-dependent chloride channel, CFTR/MRP, Channel conductance-controlling ATPase, cystic fibrosis transmembrane conductance regulator, cystic fibrosis transmembrane conductance regulator (ATP-binding cassettesub-family C, member 7), cystic fibrosis transmembrane conductance regulator, ATP-binding cassette(sub-family C, member 7), dJ760C5.1, EC 3.6.3, MRP7EC 3.6.3.49, TNR-CFTR

Host Species:
Rabbit

Quantity:
0.1 mL

Gene ID (Entrez):
1080

Target Species:
Human

Isotype:
IgG

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Novus Biologicals

NBP254369G

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Antigen:
Perilipin-2/ADFP

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
PLIN2

Immunogen:
Recombinant fragment (around aa 249-376) of human Perilipin-2/ADFP protein (exact sequence is proprietary) (Uniprot: Q99541)

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
ADFP/1365

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
ADFP, Adipophilin, Adipose differentiation-related proteinadipophilin, ADRP, MGC10598, perilipin 2, perilipin-2

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
123

Target Species:
Human

Isotype:
IgG1 κ